Hydroxy Urea

DRUG4 trials

Sponsors

Beni-Suef University, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, Riphah International University, Assiut University

Conditions

Sickle Cell Anemia in ChildrenSickle Cell DiseaseSickle Cell NephropathyThalassemiaTransfusion-dependent ThalassemiaVaso-occlusive Crisis

Phase 2

Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell Anemia

CompletedNCT04301336

Beni-Suef UniversityVaso-occlusive Crisis, Sickle Cell Disease, Sickle Cell Anemia in Children

Start: 2019-11-01End: 2020-12-10Updated: 2021-01-27

Phase 4

Efficacy of Combination of Hdroxyurea and Thalidomide Over Hydroxyurea or Thalidomide in the Treatment of Transfusion Dependent Thalassemia in Children

CompletedNCT06299670

Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshTransfusion-dependent Thalassemia

Start: 2023-11-01End: 2026-01-30Updated: 2026-06-17

Unknown Phase

Safety and Efficacy of Hemoglobin F Inducers in Patients With Beta Thalassemia

RecruitingNCT07673302

Riphah International UniversityThalassemia

Start: 2026-06-20End: 2027-06-19Target: 240Updated: 2026-08-06

Clinical Utility of Urinary N-Acetyl-β-D-Glucosaminidase (NAG), Kidney Injury Molecule-1 (KIM-1), and Diffusion-Weighted Renal MRI for the Early Detection of Sickle Cell Nephropathy in Children

Not yet recruitingNCT07785752

Assiut UniversitySickle Cell Nephropathy

Start: 2026-10-01End: 2027-12-01Target: 90Updated: 2026-08-25