Hydrocortisone Sodium Succinate

DRUG17 trials

Sponsors

Karolinska University Hospital, Universita Degli Studi Di Milano Bicocca, Children's Oncology Group, Hadassah Medical Organization, Dana-Farber Cancer Institute

Conditions

Acute Leukemia of Ambiguous LineageAcute Lymphoblastic LeukaemiaAcute Lymphoblastic LeukemiaAcute lymphoblastic leukemiaAdult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1Adult T Acute Lymphoblastic LeukemiaAnn Arbor Stage II Adult Lymphoblastic LymphomaAnn Arbor Stage II Childhood Lymphoblastic Lymphoma

Phase 1

A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat

WithdrawnNCT05320380

Children's Oncology GroupRecurrent Acute Myeloid Leukemia, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Mixed Phenotype Acute Leukemia +5

Start: 2023-08-01End: 2023-09-01Updated: 2023-09-01

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

RecruitingNCT06247787

Children's Oncology GroupRecurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Myelodysplastic Syndrome, Recurrent Juvenile Myelomonocytic Leukemia +3

Start: 2025-02-04End: 2026-06-30Target: 36Updated: 2026-02-24

Phase 2

Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma

CompletedNCT00057811

Children's Oncology GroupChildhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma +9

Start: 2004-06-30End: 2014-07-31Updated: 2014-09-19

ALL Adult Consortium Trial: Adult ALL Trial

CompletedNCT00476190

Dana-Farber Cancer InstituteAcute Lymphoblastic Leukemia

Start: 2007-04-30End: 2020-03-31Updated: 2025-06-12

Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

CompletedNCT00720109

National Cancer Institute (NCI)Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

Start: 2008-07-14End: 2020-03-31Updated: 2020-04-13

Combination Chemotherapy in Treating Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Ohio State University Comprehensive Cancer CenterLeukemia

Start: 2009-01-31Target: 180Updated: 2014-01-10

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

CompletedNCT02828358

National Cancer Institute (NCI)Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia

Start: 2017-04-01End: 2024-12-31Updated: 2025-02-27

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

RecruitingNCT04546399

National Cancer Institute (NCI)Down Syndrome, Recurrent B Acute Lymphoblastic Leukemia

Start: 2020-12-17End: 2028-06-30Target: 461Updated: 2025-09-10

A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Active, not recruitingNCT05761171

Children's Oncology GroupRecurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage +9

Start: 2024-01-08End: 2027-12-31Target: 78Updated: 2026-03-31

ALLTogether1 - A Treatment Study Protocol of the ALLTogether Consortium for Children and Young Adults (0-45 Years of Age) with Newly Diagnosed Acute Lymphoblastic Leukaemia (ALL)

RecruitingCTIS2022-501050-11-01

Karolinska University HospitalAcute Lymphoblastic Leukaemia

Start: 2020-07-13Target: 5943Updated: 2025-12-17

Phase 3

Corticosteroid Therapy of Septic Shock - Corticus

CompletedNCT00147004

Hadassah Medical OrganizationShock, Septic

Start: 2002-03-31End: 2005-11-30Updated: 2008-04-24

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Active, not recruitingNCT02112916

National Cancer Institute (NCI)Adult T Acute Lymphoblastic Leukemia, Ann Arbor Stage II Adult Lymphoblastic Lymphoma, Ann Arbor Stage II Childhood Lymphoblastic Lymphoma +5

Start: 2014-10-04End: 2026-09-16Updated: 2025-12-01

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

Active, not recruitingNCT02883049

National Cancer Institute (NCI)B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, BCR-ABL1-Like, Central Nervous System Leukemia +1

Start: 2012-02-29End: 2026-10-03Updated: 2025-11-26

Low Dose Corticosteroid Infusion in Vasoplegia After Cardiac Surgery (CORTIVAS-CS)

Instituto do CoracaoCardiac Surgery, Vasoplegia

Start: 2020-03-31End: 2021-03-31Target: 140Updated: 2020-03-10

International phase 3 trial in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) testing imatinib in combination with two different cytotoxic chemotherapy backbones

Active, not recruitingCTIS2024-515499-12-00

Universita Degli Studi Di Milano BicoccaAcute lymphoblastic leukemia

Start: 2017-10-02Target: 306Updated: 2024-11-12

Phase 4

Mesalazine With Hydrocortisone Sodium Succinate Enema for 4-Week Treatment in Patients With Ulcerative Colitis

Xijing Hospital of Digestive DiseasesUlcerative Colitis, Unspecified

Start: 2017-05-31End: 2018-03-31Target: 528Updated: 2017-04-12

Unknown Phase

Prospective Randomized Study of Glucocorticoids in the Impact of the Liver Function and the Prognosis After Hepatectomy of HCC

SuspendedNCT01608945

Eastern Hepatobiliary Surgery HospitalSome Studies Shows That the Steroid Can Reduce the Injury of the I/R of the Liver

Start: 2008-04-30Updated: 2012-05-31

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