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Hydrocortisone placebo

DRUG2 trials

Sponsors

Crinetics Pharmaceuticals Inc., Emory University

Conditions

Sepsis• ACTH-Dependent Cushing’s Syndrome. • Pituitary-dependent Cushing´s syndrome.

Phase 2

A Multicenter, Phase 2/3, Dose Range Finding Study to Evaluate the Efficacy and Safety of Atumelnant in Adults with ACTH-Dependent Cushing’s Syndrome (ADCS) Including an Open-Label Extension for Long-Term Assessment. (EQUILIBRIUM-ADCS)
Not yet recruitingCTIS2025-522648-42-01
Crinetics Pharmaceuticals Inc.• ACTH-Dependent Cushing’s Syndrome. • Pituitary-dependent Cushing´s syndrome.
Target: 25Updated: 2026-09-29

Phase 3

Vitamin C, Thiamine, and Steroids in Sepsis
CompletedNCT03509350
Emory UniversitySepsis
Start: 2018-08-22End: 2020-01-29Updated: 2021-04-13

Related Papers

Association of Vitamin C, Thiamine, and Hydrocortisone Infusion With Long-term Cognitive, Psychological, and Functional Outcomes in Sepsis Survivors
JAMA Network Open2023-02-2829 citations
Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis
JAMA2021-02-23259 citations
In response: Letter on update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol
Trials2020-04-212 citations
Update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol: statistical analysis plan for a prospective, multicenter, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial.
2019-12-047 citations
The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) Protocol: a prospective, multi-center, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial
Trials2019-04-0567 citations