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Hydrochlorothiazide (HCTZ) 25 milligrams.

DRUG2 trials

Sponsors

Hospital de Clinicas de Porto Alegre, Ottawa Hospital Research Institute

Conditions

Acute Heart Failure (AHF)Congestive Heart Failure AcuteDiuretic EffectHypertensionLung Ultrasonography ScorePoint-of-care Ultrasound (POCUS)Ultrasonography, Doppler

Phase 2

POcus INTERvention for Tailoring Diuretic Strategy in Acute Decompensated Heart Failure
Not yet recruitingNCT07469722
Hospital de Clinicas de Porto AlegreAcute Heart Failure (AHF), Congestive Heart Failure Acute, Diuretic Effect +3
Start: 2026-03-23End: 2028-07-01Target: 128Updated: 2026-03-18

Phase 4

SPIRO-First: A Pragmatic Primary Care-Embedded Pilot Trial of Renin-Guided First-Line Antihypertensive Therapy
Not yet recruitingNCT07687160
Ottawa Hospital Research InstituteHypertension
Start: 2026-09-01End: 2028-02-01Target: 30Updated: 2026-07-13