Hydralazine

DRUG17 trials

Conditions

Acute Heart FailureAcute StrokeBlood PressureBreast CancerCardio-Renal SyndromeCardiovascular DiseasesEndovascular ThrombectomyHeart Diseases

Early Phase 1

Assessing a Dose-Response Relationship of Hydralazine and Its Effects on DNA Methyltransferase 1 in Polycystic Kidney Disease Patients

CompletedNCT03423810

University of Kansas Medical CenterPolycystic Kidney Diseases

Start: 2018-04-23End: 2020-01-30Updated: 2020-02-26

Phase 1

Treatment of Supine Hypertension in Autonomic Failure

CompletedNCT00223717

Vanderbilt UniversityHypertension

Start: 2001-01-31End: 2017-01-31Updated: 2017-10-13

Hydralazine as a Demethylating Agent in Rectal Cancer

WithdrawnNCT00575640

University of ArkansasRectal Cancer

Start: 2004-11-30Updated: 2015-03-04

Hydralazine as Demethylating Agent in Breast Cancer

WithdrawnNCT00575978

University of ArkansasBreast Cancer

Start: 2004-06-30End: 2009-12-31Updated: 2015-03-04

Phase 2

Systolic Hypertension in the Elderly Program (SHEP) (Pilot Study)

CompletedNCT00000499

National Heart, Lung, and Blood Institute (NHLBI)Cardiovascular Diseases, Heart Diseases, Hypertension +1

Start: 1980-09-30End: 1983-05-31Updated: 2013-11-26

Randomized Controlled Trial of Labetalol Versus Hydralazine for Severe Hypertension in Obstetric Patients.

CompletedNCT02050529

Dow University of Health SciencesHydralazine Adverse Reaction, Hypertension, Pregnancy Induced, Pre-eclampsia +1

Start: 2012-10-31End: 2015-03-31Updated: 2018-10-26

Blood Pressure After Endovascular Stroke Therapy-II

CompletedNCT04116112

University of CincinnatiAcute Stroke, Endovascular Thrombectomy

Start: 2020-01-17End: 2022-12-15Updated: 2023-10-12

Blood Pressure Management in Stroke Following Endovascular Treatment

CompletedNCT04484350

Hamilton Health Sciences CorporationBlood Pressure, Endovascular Thrombectomy, Mechanical Thrombectomy +2

Start: 2020-10-23End: 2023-05-04Updated: 2023-11-07

Phase 3

Hydralazine Versus Labetalol for the Management of Hypertensive Disorders of Pregnancy

CompletedNCT01538875

Saint Thomas Hospital, PanamaHypertension, Pregnancy Induced

Start: 2012-07-31End: 2013-05-31Updated: 2013-05-17

Bi Treatment With Hydralazine/Nitrates Versus Placebo in Africans Admitted With Acute Heart Failure

NCT01822808

University of Cape TownAcute Heart Failure, Left Ventricular Dysfunction

Start: 2013-01-31End: 2016-07-31Target: 500Updated: 2015-08-14

Nitrates In Combination With Hydralazine in cardiorEnal Syndrome (NICHE) Study

NCT02343393

National University Hospital, SingaporeCardio-Renal Syndrome

Start: 2015-01-31End: 2016-06-30Target: 100Updated: 2015-01-22

Phase 4

Black Education and Treatment of Hypertension (BEAT HTN)

CompletedNCT00661895

Creighton UniversityHypertension

Start: 2005-08-31End: 2009-11-30Updated: 2012-12-04

Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts

RecruitingNCT06218199

Heart Center Research, LLCHeart Failure, Congestive

Start: 2021-07-08End: 2026-12-31Target: 80Updated: 2024-01-29

Unknown Phase

Sildenafil and Exercise Capacity in Hypertension

CompletedNCT00599235

University of EdinburghHypertension

Start: 2007-03-31End: 2008-08-31Updated: 2010-04-08

Pilot Study of the Treatment of Vascular Endothelial Growth Factor(VEGF)Signaling Pathway Inhibitor-Induced Hypertension

TerminatedNCT00607477

University of ChicagoTreatment Induced Hypertension

Start: 2008-01-31End: 2009-01-31Updated: 2014-06-10

Changes in Central Arterial Pressure When Comparing ACOG Hypertensive Urgency Protocols

WithdrawnNCT02933593

St. Louis UniversityHypertension

Start: 2016-08-31End: 2017-01-31Updated: 2017-11-13

Efficacy of Nifedipine Versus Hydralazine in Management of Severe Hypertension in Pregnancy

CompletedNCT04435210

Adebayo Joshua AdeniyiHypertension

Start: 2018-08-13End: 2019-02-20Updated: 2020-06-17

JAMA2023-09-05102 citations

Design of the BEST‐II Randomized Clinical Trial

Stroke Vascular and Interventional Neurology2022-05-014 citations

N-Terminal pro BNP and Galectin-3 are Prognostic Biomarkers of Acute Heart Failure in Sub-Saharan Africa: Lessons from the BAHEF Trial

ESC Heart Failure2020-11-289 citations

Efficacy of nifedipine versus hydralazine in the management of severe hypertension in pregnancy: A randomised controlled trial

Nigerian Postgraduate Medical Journal2020-01-0112 citations

Bi Treatment with Hydralazine/Nitrates vs. Placebo in Africans Admitted with Acute HEart Failure (BA-HEF)

European Journal of Heart Failure2016-05-2012 citations