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HRS-4508

DRUG2 trials

Sponsors

Fudan University, Jiangsu HengRui Medicine Co., Ltd.

Conditions

Advanced Solid TumorsBreast CancerBreast NeoplasmBreast TumorsEarly-stage Breast CancerHER2-negative Breast CancerHER2-positive Breast CancerHormone Receptor Negative Tumor

Phase 1

A Clinical Study of the Safety, Tolerability, Pharmacokinetics, and Initial Efficacy of HRS-4508 Monotherapy in Patients With Advanced or Metastatic Solid Tumors
Not yet recruitingNCT06598735
Jiangsu HengRui Medicine Co., Ltd.Advanced Solid Tumors
Start: 2024-09-30End: 2028-06-30Target: 100Updated: 2024-09-19

Phase 2

Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy
RecruitingNCT05582499
Fudan UniversityBreast Cancer, Breast Neoplasm, Breast Tumors +7
Start: 2022-11-01End: 2028-09-30Target: 716Updated: 2025-08-22

Related Papers

Abstract GS1-04: HER2-Directed Antibody-Drug Conjugate SHR-A1811 in the Neoadjuvant Treatment of HER2-positive Early Breast Cancer: a Prospective, Randomized, Open-label, Phase 2 Trial
Clinical Cancer Research2025-06-13
Abstract P2-11-06: Neoadjuvant chemotherapy plus camrelizumab vs. chemotherapy in patients with locally advanced immunomodulatory triple-negative breast cancer: a prospective, randomized, open-label, phase 2 trial
Clinical Cancer Research2025-06-13
Rational and trial design of FASCINATE-N: a prospective, randomized, precision-based umbrella trial
Therapeutic Advances in Medical Oncology2024-01-017 citations