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HPC,A Infusion

BIOLOGICAL2 trials

Sponsors

St. Jude Children's Research Hospital

Conditions

Acute Lymphoblastic Leukemia (ALL)Acute Myeloid Leukemia (AML)Chronic Myeloid Leukemia (CML)Juvenile Myelomonocytic Leukemia (JMML)LeukemiaLymphomaMyelodysplastic Syndrome (MDS)Myeloid Sarcoma

Phase 2

Haploidentical Donor Hematopoietic Progenitor Cell and NK Cell Transplantation for Hematologic Malignancy
CompletedNCT01807611
St. Jude Children's Research HospitalLeukemia, Lymphoma
Start: 2013-05-16End: 2021-09-27Updated: 2022-10-31
Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation
Active, not recruitingNCT02790515
St. Jude Children's Research HospitalAcute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML) +4
Start: 2016-07-14End: 2026-07-01Updated: 2025-08-12

Related Papers

Memory T-cell enriched haploidentical transplantation with NK cell addback results in promising long-term outcomes: a phase II trial.
2024-06-277 citations
CD45RA-Depleted Haploidentical Transplantation Combined with NK Cell Addback Results in Promising Long-Term Outcomes in Pediatric Patients with High-Risk Hematologic Malignancies
Blood2021-11-055 citations
Sequential Infusion of Tcrαβ- and CD45RA-Depleted Haploidentical Progenitor Cells Is Safe and Allows for Rapid Immune Reconstitution in Pediatric Patients with Recurrent Hematological Malignancies
Blood2018-11-29