HLX208
Sponsors
Shanghai Henlius Biotech
Conditions
ATCAdvanced MelanomaAnaplastic Thyroid CancerBrain Tumor, PrimaryCRCECDErdheim-Chester DiseaseLCH
Phase 1
The Efficacy and Safety of HLX208 in Advanced Anaplastic Thyroid Cancer (ATC) With BRAF V600 Mutation
NCT05102292
Start: 2021-12-10End: 2024-12-30Target: 25Updated: 2023-08-21
Study on Food Influence and Drug-drug Interaction of HLX208 Tablets in Chinese Healthy Subjects
CompletedNCT05902728
Start: 2023-07-04End: 2023-12-19Updated: 2024-04-05
Phase 2
The Efficacy of HLX208 (BRAF V600E Inhibitor) With Cetuximab for Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation After First-line Treatment
NCT04984369
Start: 2021-08-11End: 2025-01-15Target: 50Updated: 2023-08-21
A Phase II Clinical Trial to Evaluate HLX208 in Advanced Non-small Cell Lung Cancer Patients With BRAF V600 Mutation
NCT05065398
Start: 2021-11-15End: 2023-12-30Target: 20Updated: 2022-01-21
The Efficacy and Safety of HLX208 in Adult Langerhans Cell Histiocytosis (LCH) and Erdheim-Chester Disease (ECD) With BRAF V600E Mutation
NCT05092815
Start: 2021-12-06End: 2024-10-30Target: 25Updated: 2023-08-08
The Efficacy of HLX208 (BRAF V600E Inhibitor) for Refractory Primary Brain Tumors With BRAF Mutation After First-line Treatment
NCT05092802
Start: 2021-12-23End: 2024-05-30Target: 40Updated: 2022-05-03
A Phase II Clinical Trial to Evaluate HLX208 in Advanced Melanoma Patients With BRAF V600 Mutation
NCT05114603
Start: 2022-03-21End: 2024-08-30Target: 30Updated: 2022-05-03
The Efficacy and Safety of HLX208 in Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation
NCT05127759
Start: 2022-03-23End: 2025-06-28Target: 25Updated: 2023-08-08
A Phase II Clinical Trial to Evaluate HLX208 in Advanced Solid Tumor Patients With BRAF V600 Mutation
NCT05528406
Start: 2022-10-20End: 2025-06-01Target: 30Updated: 2022-09-06