Histakut Dimetindenmaleat 1 mg/ml Injektionslösung

DRUG3 trials

Sponsors

Deutsches Zentrum Fuer Neurodegenerative Erkrankungen e.V., Charite Universitaetsmedizin Berlin KöR

Conditions

Solid organ transplantation (Kidney)Solid organ transplantation (Liver)Sporadic Amyotrophic Lateral Sclerosis

Phase 1

A Phase I/IIa open label single ascending dose study to investigate the safety and tolerability of regulatory T cells as an adjunctive therapy in deceased-donor kidney recipients - ProTreg

RecruitingCTIS2024-514398-23-00

Charite Universitaetsmedizin Berlin KöRSolid organ transplantation (Kidney)

Start: 2024-06-10Target: 27Updated: 2025-09-10

A Phase I/IIa open label single ascending dose study to assess safety and tolerability of regulatory T cells to promote discontinuation of tacrolimus monotherapy in liver transplant recipients - LiveTreg

RecruitingCTIS2023-508261-32-00

Charite Universitaetsmedizin Berlin KöRSolid organ transplantation (Liver)

Start: 2025-07-21Target: 27Updated: 2025-08-14

Phase 2

B-cell depletion for the treatment of patients with amyotrophic lateral sclerosis (ALS) - A Randomized, Double-blind, Placebo controlled Pilot Study in Patients with Amyotrophic Lateral Sclerosis for the Evaluation of Efficacy and Safety of B-Cell Depletion with Rituximab (ABCD)

RecruitingCTIS2022-502743-35-00

Deutsches Zentrum Fuer Neurodegenerative Erkrankungen e.V.Sporadic Amyotrophic Lateral Sclerosis

Start: 2024-04-22Target: 52Updated: 2025-12-19