High-Dose Rate Brachytherapy

RADIATION10 trials

Sponsors

Rutgers, The State University of New Jersey, National Cancer Institute (NCI), Sidney Kimmel Cancer Center at Thomas Jefferson University, Oslo University Hospital, Jonsson Comprehensive Cancer Center

Conditions

Advanced Cervical AdenocarcinomaAdvanced Cervical Adenosquamous CarcinomaAdvanced Cervical Squamous Cell CarcinomaAdvanced Vaginal AdenocarcinomaAdvanced Vaginal Adenosquamous CarcinomaAdvanced Vaginal Squamous Cell CarcinomaCervical AdenocarcinomaCervical Adenosquamous Carcinoma

Phase 1

Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer

Active, not recruitingNCT02595879

National Cancer Institute (NCI)Advanced Cervical Adenocarcinoma, Advanced Cervical Adenosquamous Carcinoma, Advanced Cervical Squamous Cell Carcinoma +10

Start: 2019-09-18End: 2026-04-29Updated: 2025-11-13

Phase 2

Accelerated Partial Breast Radiation Therapy Using High-Dose Rate Brachytherapy in Treating Patients With Early Stage Breast Cancer After Surgery

CompletedNCT02526498

Rutgers, The State University of New JerseyDuctal Breast Carcinoma In Situ, Estrogen Receptor Positive, Invasive Breast Carcinoma +4

Start: 2015-07-15End: 2021-03-31Updated: 2023-05-15

Comparison of High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy for the Treatment of Localized Prostate Cancer

Active, not recruitingNCT04253483

Rutgers, The State University of New JerseyStage IIA Prostate Cancer AJCC v8, Stage IIB Prostate Cancer AJCC v8, Stage IIC Prostate Cancer AJCC v8 +2

Start: 2019-07-17End: 2027-09-01Updated: 2025-09-17

Hypofractionated Radiotherapy for the Treatment of Locally Advanced Cervical Cancer in Uganda

RecruitingNCT07276360

Uganda Cancer InstituteCervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Cancer +2

Start: 2026-03-11End: 2029-01-02Target: 278Updated: 2026-03-27

Unknown Phase

Hyperthermia and High Dose Rate Radiation Therapy in Treating Patients With Recurrent Prostate Cancer After Radiation

CompletedNCT02899221

Sidney Kimmel Cancer Center at Thomas Jefferson UniversityRecurrent Prostate Carcinoma

Start: 2017-03-21End: 2025-10-29Updated: 2026-02-20

Experiences With HDR-brachytherapy in Norway

CompletedNCT03162523

Oslo University HospitalProstate Cancer

Start: 2004-01-31End: 2016-10-15Updated: 2017-05-25

Focal Radiation Therapy for the Treatment of Low or Intermediate-Risk Prostate Cancer

WithdrawnNCT04399824

Jonsson Comprehensive Cancer CenterProstate Adenocarcinoma, Stage IIA Prostate Cancer AJCC v8, Stage IIB Prostate Cancer AJCC v8 +3

Start: 2020-04-03End: 2020-04-03Updated: 2020-11-06

Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer

RecruitingNCT04725903

Emory UniversityStage IIIA Prostate Cancer AJCC v8, Stage IIIB Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8 +1

Start: 2021-02-01End: 2027-12-31Target: 30Updated: 2026-02-17

High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma

RecruitingNCT04945642

Jonsson Comprehensive Cancer CenterProstate Adenocarcinoma, Stage IIB Prostate Cancer American Joint Committee on Cancer (AJCC) v8, Stage IIC Prostate Cancer AJCC v8 +5

Start: 2021-08-20End: 2027-07-01Target: 52Updated: 2025-07-15

Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer

Not yet recruitingNCT07468903

Jonsson Comprehensive Cancer CenterProstate Adenocarcinoma, Stage II Prostate Cancer AJCC v8, Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8

Start: 2026-04-04End: 2032-04-04Target: 45Updated: 2026-03-19

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