High-dose methotrexate

DRUG4 trials

Sponsors

Federal Research Institute of Pediatric Hematology, Oncology and Immunology, St. Jude Children's Research Hospital, Protherics Medicines Development Limited, Wake Forest University Health Sciences

Conditions

Acute Kidney InjuryAcute Lymphoblastic LeukemiaChildhood Acute Lymphoblastic LeukemiaDrug ToxicityLeukemia, B-CellLeukemia, T-CellLymphoma, Non-Hodgkin'sOsteosarcoma in Adolescents and Young Adults

Phase 2

Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma

TerminatedNCT02518750

St. Jude Children's Research HospitalAcute Lymphoblastic Leukemia, Leukemia, B-Cell, Leukemia, T-Cell +1

Start: 2016-11-23End: 2018-03-11Updated: 2019-04-03

The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma

Not yet recruitingNCT07560826

Wake Forest University Health SciencesOsteosarcoma in Adolescents and Young Adults, Osteosarcoma in Children

Start: 2026-06-01End: 2028-12-01Target: 46Updated: 2026-05-01

Unknown Phase

Childhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2008

Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyChildhood Acute Lymphoblastic Leukemia

Start: 2008-02-29End: 2020-07-31Target: 3000Updated: 2020-02-05

Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate

Protherics Medicines Development LimitedAcute Kidney Injury, Drug Toxicity

Start: 2022-04-01End: 2024-12-31Target: 1000Updated: 2024-05-10