High-Dose Influenza Vaccine

BIOLOGICAL4 trials

Sponsors

Saad Jamshed MD, Oriol Manuel, Tor Biering-Sørensen, Korea University Guro Hospital

Conditions

CancerImmune ResponseInfluenzaInfluenza VaccinesInfluenza Viral InfectionsMicrobiomeOrgan Transplantation

Phase 2

Study Comparing High-Dose Flu Vaccine to Standard Vaccine in Cancer Patients Less Than 65 Receiving Chemotherapy

CompletedNCT01666782

Saad Jamshed MDCancer, Influenza Viral Infections

Start: 2012-08-31End: 2015-12-31Updated: 2016-06-24

Reducing the Burden of Influenza After Solid-Organ Transplantation

CompletedNCT03699839

Oriol ManuelInfluenza, Organ Transplantation

Start: 2018-10-26End: 2020-08-15Updated: 2020-12-17

Phase 4

Pooled Analysis of Methodologically Harmonized Pragmatic Randomized Trials of High-Dose vs. Standard-Dose Influenza Vaccine Against Severe Clinical Outcomes

CompletedNCT06506812

Tor Biering-SørensenInfluenza

Start: 2025-05-31End: 2025-08-31Updated: 2025-09-12

Comparative Immunologic Mechanisms and Microbiome Interactions Following Different Influenza Vaccine Formulations in Older Adults

CompletedNCT07805837

Korea University Guro HospitalImmune Response, Influenza, Influenza Vaccines +1

Start: 2025-10-25End: 2026-08-31Updated: 2026-09-04

Related Papers

Effectiveness of high-dose influenza vaccine against hospitalisations in older adults (FLUNITY-HD): an individual-level pooled analysis.

2025-10-17

Immunogenicity of High-Dose Versus MF59-Adjuvanted Versus Standard Influenza Vaccine in Solid Organ Transplant Recipients: The Swiss/Spanish Trial in Solid Organ Transplantation on Prevention of Influenza (STOP-FLU Trial)

Clinical Infectious Diseases2023-08-1616 citations

Randomized study comparing high-dose (HD) influenza vaccine to standard-dose (SD) influenza vaccine in patients with breast cancer age < 65 receiving chemotherapy.

Journal of Clinical Oncology2017-05-20

Improved immunogenicity of high-dose influenza vaccine compared to standard-dose influenza vaccine in adult oncology patients younger than 65 years receiving chemotherapy: A pilot randomized clinical trial.

2015-12-2219 citations

Randomized pilot study comparing high-dose (HD) influenza vaccine to standard-dose (SD) influenza vaccine in adult oncology patients younger than 65 receiving chemotherapy.

Journal of Clinical Oncology2015-05-20