High-dose Cyclophosphamide

DRUG5 trials

Sponsors

Rambam Health Care Campus, University of Arkansas, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University, University of Nebraska

Conditions

Crohn DiseaseCrohn's DiseaseGraft-versus-Host Disease (GVHD)Hematological MalignanciesMultiple MyelomaNon-Hodgkin's Lymphoma

Phase 1

High-dose Cyclophosphamide for Severe Refractory Crohn Disease

WithdrawnNCT01836289

Johns Hopkins UniversityCrohn Disease, Crohn's Disease

Start: 2015-03-31End: 2018-03-31Updated: 2018-08-13

Phase 2

High Dose CHOP in Lymphoma

CompletedNCT00192764

Rambam Health Care CampusNon-Hodgkin's Lymphoma

Start: 1996-12-31End: 2010-09-30Target: 45Updated: 2010-09-22

UARK 89-001 Phase II Study of Intensive TOTAL THERAPY For Untreated or Minimally Treated Patients With Multiple Myeloma

CompletedNCT00580372

University of ArkansasMultiple Myeloma

Start: 2002-08-31End: 2015-10-31Updated: 2016-09-20

R-ICE and High-Dose Cyclophosphamide With PET/CT for Diffuse Large B-Cell Non-Hodgkin's Lymphoma

TerminatedNCT00809341

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNon-Hodgkin's Lymphoma

Start: 2009-01-31End: 2014-04-30Updated: 2018-09-25

Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation

RecruitingNCT06799195

University of NebraskaGraft-versus-Host Disease (GVHD), Hematological Malignancies

Start: 2025-06-23End: 2031-11-30Target: 126Updated: 2025-12-15

Related Papers

Long-Term Follow-Up of Patients With Multiple Myeloma Treated on Earlier Total Therapy Protocols

JAMA Oncology2025-06-051 citations

Curability of multiple myeloma (MM) based on relative survival rate (RSR) in patients (pts) treated on earlier total therapy (TT) protocols.

Journal of Clinical Oncology2023-06-011 citations