Herzuma 150 mg powder for concentrate for solution for infusion
Sponsors
AstraZeneca AB, Daiichi Sankyo Inc.
Conditions
Early stage HER2-positive breast cancer (T stage >= T3Locally Advanced or Metastatic HER2 positive Gastric or Gastroesophageal Junction CancerUnresectablelymph node positiveor inflammatory)
Phase 3
A Phase 3 Open-label Trial of Neoadjuvant Trastuzumab Deruxtecan (TDXd) Monotherapy or T-DXd followed by THP Compared to ddAC-THP in Participants with High-risk HER2-positive Early-stage Breast Cancer (DESTINY-Breast11)
Active, not recruitingCTIS2023-505210-18-00
Start: 2021-12-17Target: 280Updated: 2025-02-13
A Multicenter, Randomized, Open-Label, Phase 3 Trial of Trastuzumab Deruxtecan (Enhertu®) Plus Chemotherapy Plus or Minus Pembrolizumab versus Chemotherapy Plus Trastuzumab Plus Or Minus Pembrolizumab as First-Line Treatment in Participants with Unresectable, Locally Advanced or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (GEJ) Cancer (DESTINY-Gastric05)
RecruitingCTIS2024-513122-27-00
Start: 2025-06-10Target: 214Updated: 2025-11-07