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hepatic arterial infusion chemotherapy (HAIC)

PROCEDURE7 trials

Sponsors

West China Hospital, Tongji Hospital, Shandong Cancer Hospital and Institute, Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University

Conditions

BCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaColorectal CancerColorectal Cancer Liver Metastases (CRLM)Colorectal Liver Metastasis (CRLM)DurvalumabHAICHepatic Arterial Infusion Chemotherapy

Phase 2

Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma: a Phase 2 Study(HAIC-quad Trial)
RecruitingNCT06859684
West China HospitalDurvalumab, HAIC, Intrahepatic Cholangiocarcinoma (Icc)
Start: 2025-03-01End: 2027-03-06Target: 25Updated: 2026-03-09
FOLFOX-HAIC as Conversion Treatment for Initially Unresectable Colorectal Liver Metastasis
RecruitingNCT06988852
Tongji HospitalColorectal Liver Metastasis (CRLM)
Start: 2023-05-01End: 2030-12-31Target: 300Updated: 2025-05-25
BITS-TO-HCC Study: HAIC+Iparomlimab/Tuvonralimab + Bevacizumab + SBRT for BCLC-C HCC With PVTT and/or Oligometastases
RecruitingNCT07062055
Shandong Cancer Hospital and InstituteHepatic Artery Infusion Chemotherapy, Hepatocellular Carcinoma, Immunotherapy +3
Start: 2025-07-25End: 2029-07-25Target: 54Updated: 2026-05-08
HAIC Plus Systemic Chemotherapy, Lenvatinib and Toripalimab in Advanced ICC
CompletedNCT07304388
Sun Yat-sen UniversityIntrahepatic Cholangiocarcinoma (Icc)
Start: 2023-02-10End: 2025-06-01Updated: 2025-12-30
FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma
Not yet recruitingNCT07353827
Sun Yat-sen UniversityHepatic Arterial Infusion Chemotherapy, Intrahepatic Cholangiocarcinoma (Icc)
Start: 2026-02-01End: 2028-12-31Target: 36Updated: 2026-01-20
Hepatic Arterial Infusion of Liposomal Irinotecan Plus Oxaliplatin and Capecitabine as Adjuvant Therapy for Colorectal Cancer Liver Metastases
Not yet recruitingNCT07570914
Tianjin Medical University Cancer Institute and HospitalColorectal Cancer, Colorectal Cancer Liver Metastases (CRLM), Liver Metastasis
Start: 2026-05-30End: 2032-05-30Target: 28Updated: 2026-05-06

Unknown Phase

Using Machine Learning to Identify Responders to TACE or HAIC for uHCC
CompletedNCT07368530
First Affiliated Hospital, Sun Yat-Sen UniversityBCLC Stage B Hepatocellular Carcinoma, BCLC Stage C Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma (HCC)
Start: 2015-01-01End: 2025-12-31Updated: 2026-01-26