hepatic arterial infusion chemotherapy (HAIC)
Sponsors
West China Hospital, Tongji Hospital, Shandong Cancer Hospital and Institute, Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University
Conditions
BCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaColorectal CancerColorectal Cancer Liver Metastases (CRLM)Colorectal Liver Metastasis (CRLM)DurvalumabHAICHCC - Hepatocellular Carcinoma
Phase 2
Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma: a Phase 2 Study(HAIC-quad Trial)
RecruitingNCT06859684
Start: 2025-03-01End: 2027-03-06Target: 25Updated: 2026-03-09
FOLFOX-HAIC as Conversion Treatment for Initially Unresectable Colorectal Liver Metastasis
RecruitingNCT06988852
Start: 2023-05-01End: 2030-12-31Target: 300Updated: 2025-05-25
BITS-TO-HCC Study: HAIC+Iparomlimab/Tuvonralimab + Bevacizumab + Surgery/SBRT for BCLC-C HCC With PVTT and/or Oligometastases
RecruitingNCT07062055
Start: 2025-07-25End: 2029-07-25Target: 54Updated: 2026-09-04
HAIC Plus Systemic Chemotherapy, Lenvatinib and Toripalimab in Advanced ICC
CompletedNCT07304388
Start: 2023-02-10End: 2025-06-01Updated: 2025-12-30
FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma
Not yet recruitingNCT07353827
Start: 2026-02-01End: 2028-12-31Target: 36Updated: 2026-01-20
Hepatic Arterial Infusion of Liposomal Irinotecan Plus Oxaliplatin and Capecitabine as Adjuvant Therapy for Colorectal Cancer Liver Metastases
Not yet recruitingNCT07570914
Start: 2026-05-30End: 2032-05-30Target: 28Updated: 2026-05-06
Iparomlimab and Tuvonralimab With Lenvatinib, Radiotherapy, and HAIC for Hepatocellular Carcinoma With Portal Vein Tumor Thrombus
Not yet recruitingNCT07776080
Start: 2026-10-01End: 2028-10-01Target: 35Updated: 2026-08-20