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hepatic arterial infusion chemotherapy (HAIC)

PROCEDURE6 trials

Sponsors

West China Hospital, Tongji Hospital, Shandong Cancer Hospital and Institute, Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University

Conditions

BCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaColorectal Liver Metastasis (CRLM)DurvalumabHAICHepatic Arterial Infusion ChemotherapyHepatic Artery Infusion ChemotherapyHepatocellular Carcinoma

Phase 2

Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma: a Phase 2 Study(HAIC-quad Trial)
RecruitingNCT06859684
West China HospitalDurvalumab, HAIC, Intrahepatic Cholangiocarcinoma (Icc)
Start: 2025-03-01End: 2027-03-06Target: 25Updated: 2026-03-09
FOLFOX-HAIC as Conversion Treatment for Initially Unresectable Colorectal Liver Metastasis
RecruitingNCT06988852
Tongji HospitalColorectal Liver Metastasis (CRLM)
Start: 2023-05-01End: 2030-12-31Target: 300Updated: 2025-05-25
BITS-TO-HCC Study: HAIC+Iparomlimab/Tuvonralimab + Bevacizumab + SBRT for BCLC-C HCC With PVTT and/or Oligometastases
RecruitingNCT07062055
Shandong Cancer Hospital and InstituteHepatic Artery Infusion Chemotherapy, Hepatocellular Carcinoma, Immunotherapy +3
Start: 2025-07-25End: 2029-07-25Target: 54Updated: 2026-04-01
HAIC Plus Systemic Chemotherapy, Lenvatinib and Toripalimab in Advanced ICC
CompletedNCT07304388
Sun Yat-sen UniversityIntrahepatic Cholangiocarcinoma (Icc)
Start: 2023-02-10End: 2025-06-01Updated: 2025-12-30
FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma
Not yet recruitingNCT07353827
Sun Yat-sen UniversityHepatic Arterial Infusion Chemotherapy, Intrahepatic Cholangiocarcinoma (Icc)
Start: 2026-02-01End: 2028-12-31Target: 36Updated: 2026-01-20

Unknown Phase

Using Machine Learning to Identify Responders to TACE or HAIC for uHCC
CompletedNCT07368530
First Affiliated Hospital, Sun Yat-Sen UniversityBCLC Stage B Hepatocellular Carcinoma, BCLC Stage C Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma (HCC)
Start: 2015-01-01End: 2025-12-31Updated: 2026-01-26