Hemlibra 150 mg/mL solution for injection
Sponsors
F. Hoffmann-La Roche AG, Universitair Medisch Centrum Utrecht, HZRM Haemophilie-Zentrum Rhein Main GmbH, Emory University
Conditions
Congenital Haemophilia AHaemophilia AHemophilia AMild or moderate hemophilia A without FVIII inhibitorsSevere or Moderate Hemophilia AType 3 Von Willebrand Disease
Phase 3
A phase IIIb, Multicenter, Open-Label, Single-Arm Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Patients From Birth to 12 Months of Age with Hemophilia A without Inhibitors
Active, not recruitingCTIS2023-505964-13-00
Start: 2021-03-09Target: 31Updated: 2025-10-31
Pharmacokinetic-guided dosing of emicizumab in congenital haemophilia A patients – The DosEmi study
RecruitingCTIS2024-515528-35-00
Start: 2022-09-08Target: 135Updated: 2025-12-22
A Multicenter, Open-Label Study to Evaluate the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Emicizumab in Patients with Mild or Moderate Hemophilia A without FVIII Inhibitors
Active, not recruitingCTIS2023-506610-52-00
Start: 2020-06-24Target: 22Updated: 2025-10-31
A Phase III, Multicenter, Open-Label Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Emicizumab Prophylaxis in Patients with Type 3 Von Willebrand Disease
RecruitingCTIS2024-515622-80-00
Start: 2025-06-04Target: 47Updated: 2025-06-27
Phase 4
A Multicenter, Open-Label Phase IV Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes, in Participants Aged ≥13 and < 70 Years with Severe or Moderate Hemophilia a Without FVIII Inhibitors on Emicizumab Prophylaxis
Active, not recruitingCTIS2023-505747-40-00
Start: 2022-04-20Target: 45Updated: 2025-10-31
MOdern Treatment of Inhibitor-PositiVe PATiEnts with Haemophilia A – An International Low-Interventional Pragmatic Investigator Initiated Trial
RecruitingCTIS2024-516741-39-00
Start: 2020-01-14Target: 22Updated: 2025-10-28