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HDR brachytherapy

RADIATION9 trials

Sponsors

University of California, San Francisco, National Institute of Oncology, Hungary, Albert J. Chang, Sunnybrook Health Sciences Centre, Mid and South Essex NHS Foundation Trust

Conditions

Adenocarcinoma of ProstateAdvanced Prostate CancerCervical CancerLocally Recurrent Prostate CancerProstate AdenocarcinomaProstate CancerProstate Cancer Metastatic DiseaseProstate Cancer Recurrent

Phase 1

Safety and Efficacy of 21 Gy, 23 Gy and 25 Gy for High Dose Rate (HDR) Prostate Brachytherapy
RecruitingNCT03424850
Washington University School of MedicineProstate Cancer, Prostate Neoplasm
Start: 2018-02-27End: 2030-02-28Target: 36Updated: 2026-03-11

Phase 2

HDR vs LDR Brachytherapy as Monotherapy in the Treatment of Localized Prostate Cancer.
NCT02258087
National Institute of Oncology, HungaryAdenocarcinoma of Prostate
Start: 2014-09-30End: 2019-09-30Target: 50Updated: 2014-10-07
EBRT and HDR Brachytherapy for Unfavorable-intermediate, High, and Very High-risk Prostate Cancer
RecruitingNCT04465500
University of VirginiaProstate Adenocarcinoma, Prostate Cancer
Start: 2020-07-30End: 2029-01-01Target: 60Updated: 2024-05-13

Unknown Phase

Pilot Study of a Catheter-based Ultrasound Hyperthermia System
TerminatedNCT00911079
University of California, San FranciscoCervical Cancer, Prostate Cancer
Start: 2009-12-18End: 2020-07-23Updated: 2021-07-07
Hypofractionated Whole Pelvic Radiotherapy of the Prostate
WithdrawnNCT02546427
Albert J. ChangProstate Cancer
Start: 2016-12-09End: 2022-06-30Updated: 2018-02-12
Pilot Study of Whole Gland Salvage HDR Prostate Brachytherapy for Locally Recurrent Prostate Cancer
Active, not recruitingNCT02560181
Sunnybrook Health Sciences CentreProstate Cancer Recurrent
Start: 2014-08-31End: 2027-08-30Updated: 2024-11-27
Timing of HDR With EBRT in Localised Prostate Cancer,Toxicity and Quality of Life Assessment
CompletedNCT02618161
Mid and South Essex NHS Foundation TrustProstate Cancer
Start: 2014-09-30End: 2018-11-30Updated: 2020-12-22
Focal Salvage HDR Brachytherapy for Locally Recurrent Prostate Cancer in Patients Treated With Prior Radiotherapy
Active, not recruitingNCT03312972
Loyola UniversityLocally Recurrent Prostate Cancer
Start: 2017-08-28End: 2026-07-31Target: 50Updated: 2025-09-24
Lab Research Using Mini-tumors to Study Prostate Cancer Treatments
Not yet recruitingNCT07004582
Maastricht Radiation OncologyAdvanced Prostate Cancer, Prostate Cancer, Prostate Cancer Metastatic Disease +1
Start: 2026-02-10End: 2031-12-30Target: 600Updated: 2026-01-27

Related Papers

Decipher risk stratification of radiorecurrent prostate cancer: Correlative analysis of the F-SHARP trial of salvage reirradiation.
Journal of Clinical Oncology2025-02-102 citations
Alterations of Sexual and Erectile Functions after Brachytherapy for Prostate Cancer Based on Patient-Reported Questionnaires
Prostate Cancer2024-01-251 citations
Single fraction of HDR brachytherapy for prostate cancer: Results of the SiFEPI phase II prospective trial.
2022-08-189 citations
A multi-institutional phase I/II trial of focal salvage high-dose-rate brachytherapy for locally recurrent prostate cancer in patients treated with prior radiotherapy (F-SHARP).
Journal of Clinical Oncology2021-02-201 citations
Timing of high-dose rate brachytherapy with external beam radiotherapy in intermediate and high-risk localized prostate cancer (THEPCA) patients and its effects on toxicity and quality of life: Results of a randomized feasibility trial.
Journal of Clinical Oncology2021-02-20