HCTZ

DRUG11 trials

Sponsors

Novartis, Novartis Pharmaceuticals, Forest Laboratories, University of New Mexico, Boehringer Ingelheim

Conditions

AgingHealthyHigh Blood PressureHypertensionProteinuriaSedentary LifestyleType 2 Diabetes MellitusType II Diabetes

Early Phase 1

Epithelial Sodium Channel (ENaC) as a Novel Mechanism for Hypertension and Volume Expansion in Type 2 Diabetes

TerminatedNCT01804777

University of New MexicoHypertension, Proteinuria, Type II Diabetes

Start: 2013-03-31End: 2014-12-31Updated: 2018-05-11

Phase 1

Telmisartan/Hydrochlorothiazide (HCTZ) Fixed Dose Combination Compared to Its Monocomponents in Healthy Subjects

CompletedNCT02176512

Boehringer IngelheimHealthy

Start: 1998-09-30Updated: 2014-07-08

Safety, Tolerability and Pharmacokinetics of Single Rising and Multiple Oral Doses of Telmisartan / Hydrochlorothiazide (HCTZ) in Healthy Male Volunteers

CompletedNCT02262780

Boehringer IngelheimHealthy

Start: 2003-12-01Updated: 2023-12-08

Bioequivalence of Telmisartan/ HCTZ Fixed Dose Combination Compared With Its Monocomponents in Healthy Male Volunteers II

CompletedNCT02262858

Boehringer IngelheimHealthy

Start: 2005-08-31Updated: 2014-10-13

Phase 2

ACES - ACE Inhibitors Combined With Exercise for Seniors With Hypertension

CompletedNCT03295734

University of Alabama at BirminghamAging, Hypertension, Sedentary Lifestyle

Start: 2018-05-29End: 2024-09-19Updated: 2025-07-22

Phase 3

Pharmacogenomics of Hypertension Personalized Medicine (PGX-HT)

Ospedale San RaffaeleHypertension

Start: 2016-03-31End: 2018-11-30Target: 300Updated: 2017-08-15

Phase 4

Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Therapy in Patients With Hypertension

CompletedNCT00277472

NovartisHypertension

Start: 2005-11-30Updated: 2011-06-07

Efficacy of Valsartan/Hydrochlorothiazide Versus Amlodipine and Hydrochlorothiazide in Patients Hypertension

CompletedNCT00425997

NovartisHypertension

Start: 2006-12-31End: 2007-10-31Target: 480Updated: 2011-06-08

Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Compared to Valsartan Monotherapy or Hydrochlorothiazide Monotherapy in Elderly (>70) With Mild-moderate Hypertension.

CompletedNCT00698646

Novartis PharmaceuticalsHypertension

Start: 2008-04-30End: 2009-06-30Updated: 2011-04-19

Study of the Glycemic Effects of Nebivolol Compared With Metoprolol and HCTZ in Diabetic Hypertensive Patients

CompletedNCT00744237

Forest LaboratoriesHypertension, Type 2 Diabetes Mellitus

Start: 2008-08-31Updated: 2011-07-29

The Effects of Renin Inhibition on Fibrinolytic Balance and Endothelial Function

CompletedNCT03115853

Vanderbilt University Medical CenterHigh Blood Pressure

Start: 2009-06-30End: 2012-01-31Updated: 2017-08-25

Related Papers

Angiotensin Converting Enzyme Inhibitors Combined with Exercise for Hypertensive Seniors (The ACES Trial): Study Protocol of a Randomized Controlled Trial

Frontiers in Medicine2020-01-2210 citations