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HALAVEN 0.44 mg/ml solution for injection

DRUG6 trials

Sponsors

Enliven Therapeutics Inc., Intensity Therapeutics Inc., Intensity Therapeutics Inc., Medica Scientia Innovation Research S.L., Italian Sarcoma Group, Delcath Systems Inc.

Conditions

Advanced Solitary fibrous tumorBreast CancerColorectal Cancer and Breast CancerLeiomyosarcoma (non-uterine)Locally advanced or unresectable PIK3CA and/or PTENaltered metaplastic HR-positive/HER2-negative breast cancerLocally advanced or unresectable PIK3CA and/or PTENaltered metaplastic or non-metaplastic triple negative breast cancer.Refractory Metastatic Breast Cancer with Liver Dominant DiseaseSolid Tumors

Phase 1

Phase 2

PHASE II STUDY FOR PATIENTS WITH ADVANCED TRIPLE NEGATIVE OR METAPLASTIC HRPOSITIVE/HER2-NEGATIVE, PIK3CA/PTEN-ALTERED BREAST CANCER TREATED WITH ERIBULIN IN COMBINATION WITH MEN1611 -THE SABINA STUDY-
Active, not recruitingCTIS2024-512963-30-00
Medica Scientia Innovation Research S.L.Locally advanced or unresectable PIK3CA and/or PTENaltered metaplastic HR-positive/HER2-negative breast cancer, Locally advanced or unresectable PIK3CA and/or PTENaltered metaplastic or non-metaplastic triple negative breast cancer.
Start: 2023-05-24Target: 14Updated: 2025-11-18
ERibulin in Advanced Solitary fibrous tumor, an ItaliaN sarcoma Group phase II study (ERASING)
CompletedCTIS2024-517795-38-00
Italian Sarcoma GroupAdvanced Solitary fibrous tumor
Start: 2019-06-26End: 2025-10-13Target: 20Updated: 2024-10-01
Master Protocol: A Phase 1b / 2, Multicenter, Multi Arm Study of Evorpacept in Combination with Anti-cancer Therapies in Advanced / Metastatic Malignancies (ASPEN-09) Substudy Protocol: A Single-arm Phase 2 Multicenter Study of Evorpacept in Combination with Trastuzumab and Chemotherapy in Participants with Metastatic HER2-Positive Breast Cancer (ASPEN-09-03)
Not yet recruitingCTIS2025-522012-16-00
Alx Oncology Holdings Inc.Breast Cancer
Target: 36Updated: 2026-01-23
An Open-label, Randomized, Multi-Center Study to Evaluate the Efficacy and Safety of Induction Treatment with Melphalan/HDS Followed by Consolidation Treatment with Eribulin or Vinorelbine or Capecitabine Versus Eribulin or Vinorelbine or Capecitabine Alone in Patients with Metastatic Breast Cancer with Liver Dominant Disease
Not yet recruitingCTIS2025-521966-91-00
Delcath Systems Inc.Refractory Metastatic Breast Cancer with Liver Dominant Disease
Target: 3Updated: 2026-02-04

Phase 3