HALAVEN 0.44 mg/ml solution for injection
Sponsors
Enliven Therapeutics Inc., Intensity Therapeutics Inc., Intensity Therapeutics Inc., Medica Scientia Innovation Research S.L., Italian Sarcoma Group, Delcath Systems Inc.
Conditions
Advanced Solitary fibrous tumorBreast CancerColorectal Cancer and Breast CancerLeiomyosarcoma (non-uterine)Locally advanced or unresectable PIK3CA and/or PTENaltered metaplastic HR-positive/HER2-negative breast
cancerLocally advanced or unresectable PIK3CA and/or PTENaltered metaplastic or non-metaplastic triple negative breast
cancer.Refractory Metastatic Breast Cancer with Liver Dominant DiseaseSolid Tumors
Phase 1
Phase 2
PHASE II STUDY FOR PATIENTS WITH ADVANCED TRIPLE NEGATIVE OR METAPLASTIC HRPOSITIVE/HER2-NEGATIVE, PIK3CA/PTEN-ALTERED BREAST CANCER TREATED WITH ERIBULIN IN COMBINATION WITH MEN1611
-THE SABINA STUDY-
Active, not recruitingCTIS2024-512963-30-00
Start: 2023-05-24Target: 14Updated: 2025-11-18
ERibulin in Advanced Solitary fibrous tumor, an ItaliaN sarcoma Group phase II study (ERASING)
CompletedCTIS2024-517795-38-00
Start: 2019-06-26End: 2025-10-13Target: 20Updated: 2024-10-01
Master Protocol: A Phase 1b / 2, Multicenter, Multi Arm Study of Evorpacept in Combination with Anti-cancer Therapies in Advanced / Metastatic Malignancies (ASPEN-09)
Substudy Protocol: A Single-arm Phase 2 Multicenter Study of Evorpacept in Combination with Trastuzumab and Chemotherapy in Participants with Metastatic HER2-Positive Breast Cancer (ASPEN-09-03)
Not yet recruitingCTIS2025-522012-16-00
Target: 36Updated: 2026-01-23
An Open-label, Randomized, Multi-Center Study to Evaluate the Efficacy and Safety of Induction Treatment with Melphalan/HDS Followed by Consolidation Treatment with Eribulin or Vinorelbine or Capecitabine Versus Eribulin or Vinorelbine or Capecitabine Alone in Patients with Metastatic Breast Cancer with Liver Dominant Disease
Not yet recruitingCTIS2025-521966-91-00
Target: 3Updated: 2026-02-04