HA-WBRT-SIB

RADIATION2 trials

Sponsors

Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Sun Yat-sen University

Conditions

BevacizumabBrain MetastasesCognitive FunctionHippocampal AvoidanceLung AdenocarcinomaLung NeoplasmRadiotherapy, Intensity-ModulatedSimultaneous Integrated Boost

Phase 2

HA-WBRT-SIB for Brain Metastasis of Lung Cancer

CompletedNCT06289023

Cancer Institute and Hospital, Chinese Academy of Medical SciencesBrain Metastases, Cognitive Function, Hippocampal Avoidance +2

Start: 2016-01-01End: 2022-12-31Updated: 2024-03-01

Phase 3

Bevacizumab Plus FSRT Versus Hippocampus-Avoidant WBRT in Lung Adenocarcinoma With Extensive Brain Metastases

Not yet recruitingNCT07481786

Sun Yat-sen UniversityBevacizumab, Brain Metastases, Lung Adenocarcinoma +2

Start: 2026-03-15End: 2029-09-15Target: 220Updated: 2026-03-19

Related Papers

Hippocampal avoidance whole-brain radiotherapy with simultaneous integrated boost in lung cancer brain metastases and utility of the Hopkins verbal learning test for testing cognitive impairment in Chinese patients: a prospective phase II study

BMC Cancer2024-07-267 citations