Guanabenz capsule 4 mg in 360 mg blend 1
Sponsors
Amsterdam UMC, Amsterdam UMC Stichting
Conditions
Vanishing White MatterVanishing white matter
Phase 1
A Study to Explore the Safety, Tolerability, Pharmacokinetic Profile, and Potential Efficacy of Guanabenz in Patients With Early-Childhood Onset Vanishing White Matter (VWM)
CompletedCTIS2023-503320-89-00
Start: 2021-05-31End: 2025-12-29Target: 40Updated: 2025-11-20
An open-label, non-randomized, extension study to further investigate the long-term efficacy, safety, and tolerability of Guanabenz in patients with early childhood onset vanishing white matter (VWM)
RecruitingCTIS2024-518834-95-02
Start: 2025-12-08Target: 30Updated: 2025-11-26