GTI-2040

BIOLOGICAL9 trials

Sponsors

Aptose Biosciences Inc., National Cancer Institute (NCI), University Health Network, Toronto

Conditions

Acute Myeloid LeukemiaAcute Undifferentiated LeukemiaAdult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)Blastic Phase Chronic Myelogenous Leukemia

Phase 1

Combination of Capecitabine and GTI-2040 in the Treatment of Renal Cell Carcinoma

CompletedNCT00056173

Aptose Biosciences Inc.Carcinoma, Renal Cell, Metastases, Neoplasm

Start: 2002-03-31Target: 43Updated: 2008-01-07

GTI-2040 and High-Dose Cytarabine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia

CompletedNCT00070551

National Cancer Institute (NCI)Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) +3

Start: 2003-09-30Updated: 2013-06-04

GTI-2040 and Docetaxel in Treating Patients With Recurrent, Metastatic, or Unresectable Locally Advanced Non-Small Cell Lung Cancer, Prostate Cancer, or Other Solid Tumors

CompletedNCT00074022

National Cancer Institute (NCI)Recurrent Non-small Cell Lung Cancer, Recurrent Prostate Cancer, Stage IIIA Non-small Cell Lung Cancer +5

Start: 2003-10-31Updated: 2013-01-24

GTI-2040 and Gemcitabine in Treating Patients With Metastatic or Unresectable Solid Tumors

CompletedNCT00078962

National Cancer Institute (NCI)Unspecified Adult Solid Tumor, Protocol Specific

Start: 2004-01-31Updated: 2013-01-24

GTI-2040, Oxaliplatin, and Capecitabine in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer or Other Solid Tumors

CompletedNCT00084643

National Cancer Institute (NCI)Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IIIC Colon Cancer +6

Start: 2004-05-31Updated: 2013-03-27

GTI-2040 in Treating Patients With Relapsed, Refractory, or High-Risk Acute Leukemia, High-Grade Myelodysplastic Syndromes, or Refractory or Blastic Phase Chronic Myelogenous Leukemia

CompletedNCT00459212

National Cancer Institute (NCI)Acute Undifferentiated Leukemia, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) +13

Start: 2007-03-31Updated: 2015-12-04

Phase 2

GTI-2040 and Capecitabine in Treating Patients With Metastatic Breast Cancer

CompletedNCT00068588

National Cancer Institute (NCI)Male Breast Cancer, Recurrent Breast Cancer, Stage IV Breast Cancer

Start: 2003-10-31End: 2010-03-31Updated: 2014-10-31

GTI-2040, Docetaxel, and Prednisone in Treating Patients With Prostate Cancer

CompletedNCT00087165

University Health Network, TorontoProstate Cancer

Start: 2005-01-31End: 2006-12-31Updated: 2021-04-28

Combination of GTI-2040 and Cytarabine in the Treatment of Refractory and Relapsed Acute Myeloid Leukemia (AML)

CompletedNCT00565058

Aptose Biosciences Inc.Acute Myeloid Leukemia

Start: 2007-08-31End: 2010-02-28Updated: 2015-07-27