GSK5784283

DRUG8 trials

Sponsors

GlaxoSmithKline

Conditions

AsthmaNasal PolypsPulmonary Disease, Chronic Obstructive

Phase 1

A Comparative Study to Investigate the Difference in Blood Levels of Two Different Formulations of GSK5784283

RecruitingNCT07712393

GlaxoSmithKlineAsthma

Start: 2026-07-17End: 2027-04-26Target: 24Updated: 2026-07-29

Phase 2

A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma

Active, not recruitingNCT06748053

GlaxoSmithKlineAsthma

Start: 2025-02-10End: 2027-09-09Updated: 2026-08-12

Phase 3

A Study to Investigate the Efficacy and Safety of GSK5784283 Compared With Placebo in Participants With Uncontrolled Asthma (PERSIST ASTHMA-1)

Not yet recruitingNCT07780643

GlaxoSmithKlineAsthma

Start: 2026-08-31End: 2029-10-11Target: 514Updated: 2026-08-21

A Study to Investigate the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Moderate to Very Severe COPD (PERSIST COPD-1)

RecruitingNCT07780669

GlaxoSmithKlinePulmonary Disease, Chronic Obstructive

Start: 2026-08-27End: 2030-03-15Target: 624Updated: 2026-09-09

A Study to Investigate the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Moderate to Very Severe COPD (PERSIST COPD-2)

Not yet recruitingNCT07780656

GlaxoSmithKlinePulmonary Disease, Chronic Obstructive

Start: 2026-08-31End: 2030-03-15Target: 624Updated: 2026-08-21

A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Not yet recruitingNCT07782970

GlaxoSmithKlineNasal Polyps

Start: 2026-08-31End: 2029-10-30Target: 218Updated: 2026-08-24

A Study to Investigate the Efficacy and Safety of GSK5784283 Compared With Placebo in Participants With Uncontrolled Asthma (PERSIST ASTHMA-2)

Not yet recruitingNCT07782996

GlaxoSmithKlineAsthma

Start: 2026-08-31End: 2029-12-28Target: 370Updated: 2026-08-24

A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Not yet recruitingNCT07782957

GlaxoSmithKlineNasal Polyps

Start: 2026-08-31End: 2029-10-30Target: 218Updated: 2026-08-24