Granulocyte-colony stimulating factor (G-CSF)

DRUG7 trials

Conditions

Acute Leukemia in RemissionChronic Myeloid LeukemiaChronic Myelomonocytic LeukemiaHealthy Apheresis DonorsHodgkin LymphomaMononuclear (MNC) Cell DonorsMultiple MyelomaMyelodysplastic Syndromes

Phase 1

Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT

CompletedNCT03018223

H. Lee Moffitt Cancer Center and Research InstituteAcute Leukemia in Remission, Chronic Myeloid Leukemia, Chronic Myelomonocytic Leukemia +5

Start: 2017-01-31End: 2021-03-18Updated: 2021-09-16

Phase 2

Treatment of PTCL With Aggressive Induction Therapy Followed by Autologous SCT Using Denileukin Diftitox (Ontak)

TerminatedNCT00632827

University of California, San FranciscoPeripheral T-Cell Lymphoma

Start: 2008-07-01End: 2016-06-23Updated: 2020-04-27

Trial of Two Stem Cell Doses To Reduce Transplant Induced Symptom Burden

CompletedNCT00651937

M.D. Anderson Cancer CenterMultiple Myeloma, Primary Amyloidosis

Start: 2008-03-31End: 2016-01-31Updated: 2020-01-14

An Exploratory Safety Study to Investigate the Extent of Tumor Cell Mobilization (TCM) After Use of G-CSF Alone or G-CSF Plus Plerixafor in Multiple Myeloma (MM) Patients Who May be Poor Mobilizers of Stem Cells

CompletedNCT01753453

SanofiMultiple Myeloma

Start: 2013-06-30End: 2016-09-30Updated: 2021-02-23

Phase 3

Evaluation of Plerixafor Plus G-CSF to Mobilize and Collect 5×10^6CD34+ Cells/kg in Non-Hodgkin's Lymphoma (NHL) Patients for Autologous Transplantation

CompletedNCT01767714

SanofiNon-Hodgkin's Lymphoma

Start: 2013-04-30End: 2014-11-30Updated: 2014-12-09

Phase 4

Evaluation of Approved Weight-Based Dose Compared to Fixed Dose of Plerixafor in Patients With Non-Hodgkin's Lymphoma (NHL) Weighing Less Than 70 Kilograms

CompletedNCT01164475

Genzyme, a Sanofi CompanyNon-Hodgkin's Lymphoma

Start: 2010-10-31End: 2013-02-28Updated: 2014-02-25

Unknown Phase

An Evaluation of the Spectra Optia CMNC Collection Procedure

CompletedNCT02253160

Terumo BCTHealthy Apheresis Donors, Mononuclear (MNC) Cell Donors

Start: 2014-09-30End: 2015-01-31Updated: 2015-09-24

Blood Advances2021-02-2644 citations

A Phase II Study of Sirolimus-Based Calcineurin Inhibitor-Free Gvhd Prophylaxis after Peripheral Blood Haploidentical Transplantation with Post-Transplant Cyclophosphamide

Biology of Blood and Marrow Transplantation2020-01-233 citations

A Pilot, Exploratory, Randomized, Phase II Safety Study Evaluating Tumor Cell Mobilization and Apheresis Product Contamination in Patients Treated with Granulocyte Colony-Stimulating Factor Alone or Plus Plerixafor

Biology of Blood and Marrow Transplantation2018-08-2411 citations