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Granulocyte Colony-Stimulating Factor(G-CSF)

DRUG5 trials

Sponsors

Nanfang Hospital, Southern Medical University, Nanjing University

Conditions

Allogeneic Hematopoietic Stem Cell TransplantationConditioningFemale InfertilityMyelodysplastic SyndromeSecondary Acute Myeloid Leukemia Evolving From MDSThin Endometrium

Phase 2

G-CSF+Decitabine+BUCY vs BUCY Conditioning Regimen for RAEB-1, REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT
CompletedNCT02744742
Nanfang Hospital, Southern Medical UniversityAllogeneic Hematopoietic Stem Cell Transplantation, Conditioning, Myelodysplastic Syndrome
Start: 2016-04-18End: 2021-09-30Updated: 2022-02-14
G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for RAEB-1,REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT
NCT04713956
Nanfang Hospital, Southern Medical UniversityAllogeneic Hematopoietic Stem Cell Transplantation, Conditioning, Myelodysplastic Syndrome
Start: 2021-01-15End: 2024-07-31Target: 242Updated: 2021-01-19
G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for Secondary Acute Myeloid Leukemia Undergoing Allo-HSCT
NCT05449899
Nanfang Hospital, Southern Medical UniversityAllogeneic Hematopoietic Stem Cell Transplantation, Conditioning, Secondary Acute Myeloid Leukemia Evolving From MDS
Start: 2022-07-31End: 2024-12-31Target: 232Updated: 2022-07-08
G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for High-risk MDS Undergoing Allo-HSCT
NCT05453552
Nanfang Hospital, Southern Medical UniversityAllogeneic Hematopoietic Stem Cell Transplantation, Conditioning, Myelodysplastic Syndrome
Start: 2022-07-01End: 2024-12-31Target: 242Updated: 2023-03-21

Phase 3

Intrauterine G-CSF Infusion for Thin Endometrium
Not yet recruitingNCT07692672
Nanjing UniversityFemale Infertility, Thin Endometrium
Start: 2026-10-01End: 2029-08-01Target: 620Updated: 2026-07-09

Related Papers

The effect of granulocyte-colony stimulating factor, decitabine, and busulfan-cyclophosphamide versus busulfan-cyclophosphamide conditioning on relapse in patients with myelodysplastic syndrome or secondary acute myeloid leukaemia evolving from myelodysplastic syndrome undergoing allogeneic haematopoietic stem-cell transplantation: an open-label, multicentre, randomised, phase 3 trial.
2023-01-2319 citations
Effect of Two Conditionings on Relapse in Myelodysplastic Syndrome and Secondary Acute Myeloid Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation
Blood2022-11-15