GLM101
Sponsors
Glycomine Inc., Glycomine, Inc.
Conditions
PMM2-CDGPhosphomannomutase 2 DeficiencyPmm2-CDG
Phase 2
24-Week Study to Assess the PD, Safety, Tolerability, and PK of GLM101 in Participants With PMM2-CDG
CompletedNCT05549219
Start: 2022-11-29End: 2025-11-18Updated: 2025-12-17
A Phase 2, Randomized, Open-Label, 24-Week Study to Assess the Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of Multiple Doses of GLM101 Administered Intravenously to Adult, Adolescent and Pediatric Participants with PMM2-CDG
CompletedCTIS2024-513119-29-00
Start: 2022-12-02End: 2025-10-02Target: 19Updated: 2025-05-12
A Phase 2, Open-Label Extension Study to Assess the Safety and Efficacy of GLM101 Administered Intravenously to Participants with PMM2-CDG
RecruitingCTIS2024-512171-12-00
Start: 2024-09-27Target: 39Updated: 2025-11-05
Open-Label Extension Study to Assess GLM101 in PMM2-CDG Patients
Enrolling by invitationNCT06657859
Start: 2024-09-30End: 2029-10-01Target: 90Updated: 2026-03-02
A Phase 2b, Multicenter, Double-blind, Randomized, Placebo controlled Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 Administered Intravenously to Participants with PMM2-CDG
RecruitingCTIS2024-520109-37-00
Start: 2025-07-09Target: 45Updated: 2026-01-27