GINAKIT Cells

GENETIC2 trials

Sponsors

Baylor College of Medicine

Conditions

Neuroblastoma

Phase 1

3RD GENERATION GD2 SPECIFIC CHIMERIC ANTIGEN RECEPTOR TRANSDUCED AUTOLOGOUS NATURAL KILLER T-CELLS FOR NEUROBLASTOMA

WithdrawnNCT02439788

Baylor College of MedicineNeuroblastoma

Start: 2017-08-31End: 2030-10-31Updated: 2017-06-14

GD2 Specific CAR and Interleukin-15 Expressing Autologous NKT Cells to Treat Children With Neuroblastoma

RecruitingNCT03294954

Baylor College of MedicineNeuroblastoma

Start: 2018-01-18End: 2040-08-10Target: 70Updated: 2025-09-19

Related Papers

Hyperleukocytosis in a neuroblastoma patient after treatment with natural killer T cells expressing a GD2-specific chimeric antigen receptor and IL-15

Journal for ImmunoTherapy of Cancer2025-01-0110 citations

Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results

UNC Libraries2024-05-10

Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results.

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NKT cells coexpressing a GD2-specific chimeric antigen receptor and IL15 show enhanced in vivo persistence and antitumor activity against neuroblastoma

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Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis

Carolina Digital Repository (University of North Carolina at Chapel Hill)2021-05-076 citations

Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis.

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NKT Cells Coexpressing a GD2-Specific Chimeric Antigen Receptor and IL15 Show Enhanced <i>In Vivo</i> Persistence and Antitumor Activity against Neuroblastoma

Clinical Cancer Research2019-09-04171 citations

Invariant NKT cells as a platform for CAR immunotherapy and prevention of acute Graft‐versus‐Host Disease

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Abstract IA09: Harnessing natural and engineered properties of NKT cells for cancer immunotherapy

Cancer Immunology Research2019-02-012 citations