Gepotidacin
Sponsors
GlaxoSmithKline, Institut National de la Santé Et de la Recherche Médicale, France
Conditions
GonorrheaHealthy VolunteersInfection, BacterialInfections, BacterialUrinary Tract Infections
Phase 1
Pharmacokinetic Study of Gepotidacin in Subjects With Varying Degrees of Renal Impairment and in Subjects With Normal Renal Function
CompletedNCT02729038
Start: 2016-06-29End: 2017-06-20Updated: 2020-07-21
Pharmacokinetics (PK) Study of Gepotidacin (GSK2140944) in Adult Subjects With Varying Degrees of Hepatic Impairment and in Matched Control Subjects With Normal Hepatic Function
CompletedNCT03562117
Start: 2018-06-14End: 2018-12-26Updated: 2021-04-12
Pharmacokinetics of Gepotidacin Tablets in Adults and Adolescents Subjects
CompletedNCT04079790
Start: 2019-09-04End: 2019-11-25Updated: 2020-09-04
Penetration of the Innovative Antibiotic Gepotidacin Into Prostate and Tonsillar Tissue
CompletedNCT04484740
Start: 2021-01-29End: 2023-05-27Updated: 2025-02-20
Drug-drug Interaction Study of Gepotidacin
CompletedNCT04493931
Start: 2020-08-14End: 2020-12-21Updated: 2022-03-04
A Study to Evaluate Pharmacokinetic, Safety, Tolerability and Relative Bioavailability of Gepotidacin in Healthy Adult Male and Female Participants
CompletedNCT05271799
Start: 2022-03-01End: 2022-04-22Updated: 2023-01-30
A Study in Pediatric Participants Aged ≥2 to <12 Years With a Suspected or Confirmed Bacterial Infection or Receiving Prophylaxis Antibiotics
Not yet recruitingNCT07371429
Start: 2026-03-31End: 2027-08-23Target: 20Updated: 2026-02-12
Phase 2
Phase 3
A Study Evaluating Efficacy and Safety of Gepotidacin Compared With Ceftriaxone Plus Azithromycin in the Treatment of Uncomplicated Urogenital Gonorrhea
CompletedNCT04010539
Start: 2019-10-21End: 2023-10-10Updated: 2024-05-30
A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)
CompletedNCT04020341
Start: 2019-10-17End: 2022-11-30Updated: 2023-06-22
Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)
CompletedNCT04187144
Start: 2020-04-23End: 2022-12-01Updated: 2023-07-18
A Study to Investigate the Efficacy and Safety With Gepotidacin in Japanese Female Participants With Uncomplicated Urinary Tract Infection (Acute Cystitis)
CompletedNCT05630833
Start: 2023-01-11End: 2024-02-02Updated: 2025-03-17
A Study in Adolescent and Adult Female Participants to Evaluate Clinical Symptom Improvement and the Safety of Gepotidacin During Treatment of Uncomplicated Urinary Tract Infections (Acute Cystitis)
CompletedNCT06597344
Start: 2024-10-02End: 2025-03-10Updated: 2026-02-11
Related Papers
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