Genetically Engineered Hematopoietic Stem Progenitor Cells

BIOLOGICAL2 trials

Sponsors

Fred Hutchinson Cancer Center, City of Hope Medical Center

Conditions

Fanconi AnemiaRecurrent Hodgkin LymphomaRefractory Hodgkin Lymphoma

Phase 1

Gene Therapy for Fanconi Anemia

TerminatedNCT01331018

Fred Hutchinson Cancer CenterFanconi Anemia

Start: 2012-02-22End: 2024-02-15Updated: 2024-05-17

Phase 2

Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin Lymphoma

RecruitingNCT04871607

City of Hope Medical CenterRecurrent Hodgkin Lymphoma, Refractory Hodgkin Lymphoma

Start: 2021-11-02End: 2029-10-02Target: 33Updated: 2025-12-04

Related Papers

Anti-CD25 radioimmunotherapy with BEAM autologous hematopoietic cell transplantation conditioning in Hodgkin lymphoma

Blood Advances2021-10-1713 citations

From Bone Marrow to Mobilized Peripheral Blood Stem Cells: The Circuitous Path to Clinical Gene Therapy for Fanconi Anemia

Blood2018-11-291 citations

Gene Therapy for Fanconi Anemia in Seattle: Clinical Experience and Next Steps

Blood2016-12-0210 citations