Gemcitabin Hikma 38 mg/ml Konzentrat zur Herstellung einer Infusionslösung
Sponsors
Immunogen Inc., Jazz Pharmaceuticals Ireland Limited, Institut De Recherches Internationales Servier IRIS, Panbela Therapeutics Inc.
Conditions
BRAF and Other Selected RAS/MAPK MutationsBTC - Biliary Tract CancerLocally advancedMalignancies with Documented KRASMetastatic Pancreatic Ductal AdenocarcinomaPlatinum-sensitive epithelial ovarianfallopian tubeor primary
peritoneal cancers
Phase 1
A Phase 1b/2, Safety Lead-in and Dose-Expansion, Open label, Multicenter Trial Investigating the Safety, Tolerability, and Preliminary Activity of Ivosidenib in Combination with Durvalumab and Gemcitabine/Cisplatin as First-line Therapy in Participants with Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma with an IDH1 Mutation
RecruitingCTIS2024-514261-19-00
Start: 2025-03-24Target: 16Updated: 2025-09-19
A Phase 1/2, Open-label Study of Oral S241656 (BDTX-4933) as Monotherapy and in Combination with Other Anti-Cancer Therapies in Patients with KRAS, BRAF and Other Selected RAS/MAPK Mutation-Positive Malignancies
Not yet recruitingCTIS2025-523474-16-00
Target: 75Updated: 2026-04-22
Phase 2
Phase 3
2022-501606-35-00 – Randomized, multicenter, open-label, Phase 3 study of mirvetuximab soravtansine in combination with bevacizumab versus bevacizumab alone as maintenance therapy for patients with FRα-high recurrent platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancers who have not progressed after second-line platinum-based chemotherapy plus bevacizumab (GLORIOSA).
RecruitingCTIS2022-501606-35-01
Start: 2024-02-21Target: 110Updated: 2026-01-21
An open-label randomized trial of the efficacy and safety of zanidatamab with standard-of-care therapy against standard of-care therapy alone for advanced HER2 positive biliary tract cancer
RecruitingCTIS2023-508219-21-00
Start: 2024-09-12Target: 93Updated: 2025-12-11