Gel PKB171

DRUG2 trials

Sponsors

Prokrea Bcn S.L., Prokrea BCN, S.L.

Conditions

Maximum Tolerated DoseOligospermia and/or asthenozoospermiaPharmacokineticsSafety

Phase 1

Pentoxifylline PKB171 Gel in Healthy Females Volunteers

CompletedNCT07017114

Prokrea BCN, S.L.Maximum Tolerated Dose, Pharmacokinetics, Safety

Start: 2016-01-27End: 2016-09-21Updated: 2025-06-12

Phase 2

A multicenter, randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of a post-coital intravaginal gel of PKB171 in couples with mild male factor infertility.

RecruitingCTIS2023-503850-11-00

Prokrea Bcn S.L.Oligospermia and/or asthenozoospermia

Start: 2025-10-28Target: 732Updated: 2025-10-09