GCSF

DRUG16 trials

Sponsors

Hospira UK Ltd, Northwestern University, Massachusetts General Hospital, Tianjin SinoBiotech Ltd., National University Hospital, Singapore

Conditions

Acute Lymphoid Leukemia (ALL)Acute Myeloid Leukemia (AML)Acute-On-Chronic Liver FailureAlcoholic HepatitisCervix CancerChemotherapy-induced NeutropeniaChronic Granulomatous DiseaseDecompensated Cirrhosis

Phase 1

Rheumatoid Arthritis:Tolerance Induction by Mixed Chimerism

TerminatedNCT00282412

Northwestern UniversityRheumatoid Arthritis

Start: 2002-09-30End: 2016-06-30Updated: 2018-07-30

PCI-24781 in Combination With Doxorubicin to Treat Sarcoma

CompletedNCT01027910

Massachusetts General HospitalSarcoma

Start: 2009-02-28End: 2015-03-31Updated: 2025-07-24

Bone Marrow Sparing Image-Guided Radiation Therapy (RT) Incorporating Novel Use of GCSF and FDG-PET Imaging

TerminatedNCT04514692

Stanford UniversityCervix Cancer, Endometrial Cancer

Start: 2021-02-01End: 2023-09-27Updated: 2025-04-23

Phase 2

Meloxicam vs Placebo for Mobilization

CompletedNCT02003625

Massachusetts General HospitalHematopoietic Stem Cells, Hodgkin's Lymphoma, Multiple Myeloma +1

Start: 2013-10-31End: 2019-04-30Updated: 2020-05-18

Study of Recombinant Human Serum Albumin/Granulocyte Colony-Stimulating Factor Fusion Protein

CompletedNCT02465801

Tianjin SinoBiotech Ltd.Chemotherapy-induced Neutropenia

Start: 2014-12-16End: 2016-04-26Updated: 2017-07-18

Recombinant Human Serum Albumin/Granulocyte Colony Stimulating Factor Fusion Protein for Breast Cancer Patients

CompletedNCT03251768

Tianjin SinoBiotech Ltd.Chemotherapy-induced Neutropenia

Start: 2017-10-19End: 2019-04-24Updated: 2019-09-13

Plerixafor/G-CSF as Additional Agents for Conditioning Before HSCT in CGD Patients

Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyChronic Granulomatous Disease

Start: 2019-04-13End: 2023-01-01Target: 17Updated: 2019-09-17

A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant

Active, not recruitingNCT04872595

Memorial Sloan Kettering Cancer CenterAcute Lymphoid Leukemia (ALL), Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS)

Start: 2021-04-30End: 2026-04-30Updated: 2025-09-04

Polatuzumab Vedotin With R-GDP in Relapsed/Refractory Diffuse Large B-cell Lymphoma

Active, not recruitingNCT05498220

UNC Lineberger Comprehensive Cancer CenterDiffuse Large B-cell Lymphoma

Start: 2023-02-17End: 2026-11-07Updated: 2025-09-02

Mozobil for Autologous Hematopoietic Stem Cell Transplantation

RecruitingNCT07188090

Thomas Jefferson UniversityHodgkin Lymphoma, Multiple Myeloma, Non-hodgkin Lymphoma

Start: 2025-10-16End: 2028-06-30Target: 100Updated: 2025-11-28

Phase 3

A Phase III randomised, multicentre, double-blind, therapeutic equivalence study of biosimilar G-CSF (PLIVA/Mayne filgrastim) versus Neupogen (filgrastim-Amgen) in subjects receiving doxorubicin and docetaxel as a combination chemotherapy for breast cancer

Active, not recruitingEUCTR2007-000394-36-GB

Hospira UK LtdThis study is designed to demonstrate the therapeutic equivalence of PLIVA/Mayne filgrastim and Neupogen for the reduction in duration of neutropenia and the incidence of febrile neutropenia, in subjects receiving chemotherapy. MedDRA version: 9.1 Level: LLT Classification code 10029354 Term: Neutropenia

Start: 2007-09-07Target: 279Updated: 2019-11-25

Autologous Endothelial Progenitor Cell Therapy for Reversal of Liver Cirrhosis

National University Hospital, SingaporeEnd Stage Liver Disease

Start: 2017-08-24End: 2023-12-31Target: 66Updated: 2021-01-19

Phase 4

GCSF in Alcoholic Hepatitis

Post Graduate Institute of Medical Education and Research, ChandigarhAlcoholic Hepatitis

Start: 2017-11-19End: 2020-11-18Target: 100Updated: 2018-10-12

Unknown Phase

To Assess the Efficacy of High-Volume Plasma Exchange and GCSF Versus GCSF Alone in Patients of Acute on Chronic Liver Failure (ACLF).

WithdrawnNCT03162419

Institute of Liver and Biliary Sciences, IndiaAcute-On-Chronic Liver Failure

Start: 2017-05-01End: 2019-04-25Updated: 2018-12-03

Efficacy of Monotherapy vs Combination Therapy of Corticosteroids With GCSF in Severe Alcoholic Hepatitis Patients.

Institute of Liver and Biliary Sciences, IndiaAlcoholic Hepatitis

Start: 2019-09-07End: 2021-02-27Target: 126Updated: 2019-09-09

National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Single vs Repeated Cycle of Granulocyte Colony-Stimulating Factor (GCSF) & Darbepoetin in Early Decompensated Cirrhosis

Not yet recruitingNCT07131280

Institute of Liver and Biliary Sciences, IndiaDecompensated Cirrhosis

Start: 2025-09-30End: 2031-12-31Target: 110Updated: 2025-08-20

Related Papers

Model-based antithymocyte globulin dosing in ex vivo CD34+ selected allogeneic haematopoietic cell transplantation: a single-centre, single-arm, phase 2 study.

2025-12-01

Randomized and dose-escalation trials of recombinant human serum albumin /granulocyte colony-stimulating factor in patients with breast cancer receiving anthracycline-containing chemotherapy.

2021-03-312 citations