garadacimab
Sponsors
CSL Behring LLC, CSL Behring
Conditions
Hereditary AngioedemaHereditary Angioedema (HAE)Hereditary angioedemaHereditary angioedema (HAE)Idiopathic Pulmonary Fibrosis
Phase 2
Phase 3
A Phase 3 Open-label Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of CSL312 (Garadacimab) in the Prophylactic Treatment of Hereditary Angioedema in Pediatric Subjects 2 to 11 Years of Age
CompletedCTIS2022-502386-13-00
Start: 2024-05-10End: 2025-10-30Target: 7Updated: 2025-10-29
An Open-label Study to Evaluate the Long-term Safety and Efficacy of CSL312 (Garadacimab) in the Prophylactic Treatment of Hereditary Angioedema
CompletedCTIS2024-510777-18-00
Start: 2021-06-15End: 2025-11-20Target: 52Updated: 2025-11-28
Phase 4
Safety Study in Subjects ≥ 12 Years of Age With Hereditary Angioedema Switching to Garadacimab
CompletedNCT06806657
Start: 2025-04-28End: 2026-06-29Updated: 2026-07-23
A phase 4 open-label study to evaluate the safety after switching to CSL312 (Garadacimab) from current prophylactic HAE treatment in subjects with HAE ≥ 12 years of age
Not yet recruitingCTIS2024-517757-27-00
Target: 5Updated: 2025-10-06