Gadopiclenol

DRUG12 trials

Conditions

Blood Brain Barrier DefectBody IndicationCNS LesionCentral Nervous System DiseasesCongenital Heart DiseaseContrast Enhanced Images vs. Non-contrast ImagesGadopiclinol Enhanced Images vs. Gadobutrol Enhanced ImagesImage

Phase 1

Pharmacokinetics and Safety of Gadopiclenol in Japanese Healthy Volunteers

CompletedNCT04906005

GuerbetPharmacokinetics

Start: 2021-05-10End: 2021-07-27Updated: 2021-10-07

Phase 2

Gadopiclenol Pharmacokinetics, Safety and Efficacy in Children < 2 Years of Age

CompletedNCT05590884

GuerbetBody Indication, Central Nervous System Diseases, Pediatric Disorder

Start: 2022-09-21End: 2024-09-30Updated: 2025-10-28

Phase 3

Efficacy and Safety of Gadopiclenol for Body Magnetic Resonance Imaging (MRI)

CompletedNCT03986138

GuerbetLesion in Body Region

Start: 2019-08-27End: 2020-12-09Updated: 2025-10-27

Efficacy and Safety of Gadopiclenol for Central Nervous System (CNS) Magnetic Resonance Imaging (MRI)

CompletedNCT03996447

GuerbetBlood Brain Barrier Defect, CNS Lesion

Start: 2019-06-03End: 2020-09-11Updated: 2025-09-22

Evaluation of Gadopiclenol for Magnetic Resonance Imaging (MRI) in Japanese Adults and Children

CompletedNCT06010173

GuerbetCNS Lesion, Lesion in Body Region

Start: 2023-07-21End: 2025-03-26Updated: 2025-05-20

Comparative Effectiveness of Gadopiclenol for Evaluation of Adult Congenital Heart Anatomy and Hemodynamics

Not yet recruitingNCT06406517

University of California, San DiegoCongenital Heart Disease

Start: 2024-05-31End: 2025-06-30Target: 160Updated: 2024-05-09

Evaluation of the Efficacy and Safety of Magnetic Resonance Angiography (MRA) Using Gadopiclenol Compared to Gadoterate Meglumine in the Assessment of Steno-occlusive Disease in Adult Patients With Suspected Vascular Disease

Not yet recruitingNCT07348640

GuerbetSteno-occlusive Disease

Start: 2026-02-02End: 2027-12-31Target: 315Updated: 2026-01-20

Phase 4

Gadopiclenol in Contrast Enhanced MRI of the Prostate

RecruitingNCT06226129

Columbia UniversityProstate Cancer

Start: 2024-02-14End: 2028-02-01Target: 150Updated: 2025-10-17

Gadopiclenol vs. Gadobutrol for Dynamic Contrast-Enhanced Pituitary MRI (Magnetic Resonance Imaging)

RecruitingNCT06846853

UConn HealthContrast Enhanced Images vs. Non-contrast Images, Gadopiclinol Enhanced Images vs. Gadobutrol Enhanced Images

Start: 2025-03-01End: 2025-12-25Target: 10Updated: 2025-04-15

Randomized Comparison of Contrast Agents Gadopiclenol and Gadobutrol in the Workup of Incidental Renal and Adrenal Findings

RecruitingNCT07040865

Insel Gruppe AG, University Hospital BernSuspect Renal and Adrenal Imaging Findings

Start: 2025-08-18End: 2027-07-31Target: 104Updated: 2025-11-19

Unknown Phase

MRI Gadopiclenol Enhanced Imaging of CNS Tumors

WithdrawnNCT06127810

Medical University of South CarolinaImage

Start: 2024-12-30End: 2024-12-30Updated: 2025-02-04

Gadopiclenol vs Gadoxetate MRI for Liver Lesions

Enrolling by invitationNCT06596616

Icahn School of Medicine at Mount SinaiLiver Lesion

Start: 2024-07-01End: 2026-03-27Target: 75Updated: 2025-07-29

Related Papers

Efficacy and Safety of Half-Dose Gadopiclenol versus Full-Dose Gadobutrol for Contrast-enhanced Body MRI

Radiology2023-07-0153 citations