Fulvestrant Teva 250 mg solución inyectable en jeringa precargada EFG
Sponsors
Medica Scientia Innovation Research S.L.
Conditions
Study to evaluate the effect of metformin in the prevention of hyperglycemia
in HR[+]/HER2[–] PIK3CA-mutated advanced breast cancer patients treated
with alpelisib plus endocrine therapy. The Metallica study.Unresectable locally recurrent or metastatic hormone receptor (HR)-positive and human epidermal growth factor receptor 2 (HER2)-low/ultralow breast cancer classified as non-luminal by gene expression profiling.
Phase 2
Study to evaluate the effect of metformin in the prevention of hyperglycemia
in HR[+]/HER2[–] PIK3CA-mutated advanced breast cancer patients treated
with alpelisib plus endocrine therapy. The Metallica study.
CompletedCTIS2024-511295-33-00
Start: 2020-08-13End: 2025-03-16Target: 88Updated: 2025-02-03
A randomized phase II study to evaluate the safety and efficacy of trastuzumab deruxtecan versus CDK4/6 inhibitor-based endocrine therapy as first-line therapy of HR-positive and HER2-low/ultra-low advanced breast cancer patients classified as non-luminal subtype according to gene expression profiling (The PONTIAC Study).
RecruitingCTIS2024-512360-55-00
Start: 2025-06-30Target: 194Updated: 2026-01-16