FTC/TDF Placebo

DRUG6 trials

Sponsors

Gilead Sciences

Conditions

Acquired Immunodeficiency SyndromeChronic Hepatitis BHIVHIV InfectionsHIV-1 InfectionHepatitis B

Phase 2

Study Comparing Tenofovir Disoproxil Fumarate (TDF), Emtricitabine (FTC)/TDF, and Entecavir (ETV) in the Treatment of Chronic HBV in Subjects With Decompensated Liver Disease.

CompletedNCT00298363

Gilead SciencesChronic Hepatitis B

Start: 2006-04-30End: 2011-04-30Updated: 2013-04-25

D/C/F/TAF Versus COBI-boosted DRV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment Naive Adults

CompletedNCT01565850

Gilead SciencesAcquired Immunodeficiency Syndrome, HIV Infections

Start: 2012-04-30End: 2014-02-28Updated: 2016-04-11

Phase 3

Tenofovir Disoproxil Fumarate (Tenofovir DF) Versus Emtricitabine/Tenofovir DF in Subjects Resistant to Lamivudine

CompletedNCT00737568

Gilead SciencesHepatitis B

Start: 2008-09-30End: 2015-02-28Updated: 2016-03-11

Study to Evaluate the Safety and Efficacy of Stribild Versus Ritonavir-Boosted Atazanavir Plus Truvada in Human Immunodeficiency Virus, Type 1 (HIV-1) Infected, Antiretroviral Treatment-Naive Adults

CompletedNCT01106586

Gilead SciencesHIV, HIV Infections

Start: 2010-04-30End: 2014-09-30Updated: 2015-11-11

Safety and Efficacy of E/C/F/TDF Versus RTV-Boosted ATV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment-Naive Women

CompletedNCT01705574

Gilead SciencesAcquired Immunodeficiency Syndrome, HIV Infections

Start: 2012-10-24End: 2018-09-06Updated: 2019-09-20

Switch Study to Evaluate F/TAF in HIV-1 Positive Participants Who Are Virologically Suppressed on Regimens Containing FTC/TDF

CompletedNCT02121795

Gilead SciencesHIV-1 Infection

Start: 2014-05-06End: 2019-03-01Updated: 2020-03-12

Related Papers

HIV-1 resistance rarely observed in patients using darunavir once-daily regimens across clinical studies.

2017-11-1632 citations

Tenofovir disoproxil fumarate (TDF) vs. emtricitabine (FTC)/TDF in lamivudine resistant hepatitis B: A 5-year randomised study

Journal of Hepatology2016-08-2260 citations

Integrase inhibitor versus protease inhibitor based regimen for HIV-1 infected women (WAVES): a randomised, controlled, double-blind, phase 3 study.

2016-05-2768 citations

Efficacy and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate given as fixed-dose combinations containing emtricitabine as backbones for treatment of HIV-1 infection in virologically suppressed adults: a randomised, double-blind, active-controlled phase 3 trial.

2016-03-14114 citations

No Resistance and Improved Renal and Bone Profiles with a Single-Table Regimen of D/C/F/TAF

MD Conference Express2014-11-01

No resistance to tenofovir disoproxil fumarate through 96 weeks of treatment in patients with lamivudine-resistant chronic hepatitis B.

2014-06-1130 citations

Randomized comparison of tenofovir disoproxil fumarate vs emtricitabine and tenofovir disoproxil fumarate in patients with lamivudine-resistant chronic hepatitis B.

2013-12-22114 citations

Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial.

2012-06-01260 citations