Skip to content
FindTrial
Search trials
Search trials by condition, treatment, sponsor...
Sign In
Frozen Plasma
BIOLOGICAL
4 trials
Sponsors
Ottawa Hospital Research Institute
, University Health Network, Toronto
Conditions
Bleeding in Cardiac Surgery
Blood Coagulation Disorders
Coagulation
Coagulopathy
Massive Hemorrhage
Traumatic Hemorrhage
Phase 1
Effectiveness of Plasma Transfusions in Critical Care Patients
Completed
NCT00302965
Ottawa Hospital Research Institute
Coagulation
Start: 2005-04-30
End: 2006-12-31
Target: 70
Updated: 2008-10-21
Phase 2
Factor Replacement in Surgery
NCT04114643
University Health Network, Toronto
Bleeding in Cardiac Surgery
Start: 2019-09-24
End: 2020-12-31
Updated: 2020-11-03
Phase 3
Transfusion of Plasma Prior to Invasive Procedures Pilot Trial (TOPPIT)
NCT02561026
Ottawa Hospital Research Institute
Blood Coagulation Disorders
Start: 2016-01-31
End: 2019-02-28
Target: 80
Updated: 2018-03-30
Phase 4
Factor In the Initial Resuscitation of Severe Trauma 2 Patients
NCT04534751
University Health Network, Toronto
Coagulopathy, Massive Hemorrhage, Traumatic Hemorrhage
Start: 2021-04-01
End: 2024-01-30
Target: 350
Updated: 2022-12-05
Related Papers
Factors in the Initial Resuscitation of Patients With Severe Trauma
JAMA Network Open
2025-09-22
3 citations
Major haemorrhage: putting evidence into practice
British Journal of Haematology
2022-06-10
2 citations
Protocol for a multicentre, randomised, parallel-control, superiority trial comparing administration of clotting factor concentrates with a standard massive haemorrhage protocol in severely bleeding trauma patients: the FiiRST 2 trial (a 2020 EAST multicentre trial)
BMJ Open
2021-09-01
17 citations
Comparison of 4-Factor Prothrombin Complex Concentrate With Frozen Plasma for Management of Hemorrhage During and After Cardiac Surgery
JAMA Network Open
2021-04-01
75 citations
Transfusion of fresh frozen plasma in non-bleeding ICU patients--TOPIC trial: study protocol for a randomized controlled trial.
2011-12-23
17 citations