FOLFIRI + Cetuximab

DRUG4 trials

Sponsors

Dr. Carl Schimanski, Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD), Arbeitsgemeinschaft medikamentoese Tumortherapie, Sofia Perea, Director Clinical Trials Unit.

Conditions

Colorectal Cancer MetastaticMetastatic Colorectal Cancer

Phase 2

Influence of BRAF and PIK3K Status on the Efficacy of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFIRI) Plus Bevacizumab or Cetuximab in Patients With RAS Wild-type Metastatic Colorectal Carcinoma and < 3 Circulating Tumor Cells (CTC)

CompletedNCT01640444

Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)Colorectal Cancer Metastatic

Start: 2012-07-31End: 2018-11-30Updated: 2019-04-11

Biomarker Directed Treatment in Metastatic Colorectal Cancer

CompletedNCT01703390

Arbeitsgemeinschaft medikamentoese TumortherapieMetastatic Colorectal Cancer

Start: 2012-12-04End: 2020-07-03Updated: 2020-12-21

Phase 4

FOLFIRI in Combination With Cetuximab in the First-line Treatment of Metastatic Colorectal Cancer Including a Regular Dermal Prophylaxis to Prevent Acneiforme Follicular Exanthema

Dr. Carl SchimanskiColorectal Cancer Metastatic

Start: 2011-01-31End: 2018-03-31Target: 165Updated: 2013-12-18

Unknown Phase

RAS Switch in Patients With Metastatic RAS Native Colorectal Tumors Treated With 1st Line FOLFIRI-Cetuximab

Sofia Perea, Director Clinical Trials Unit.Colorectal Cancer Metastatic

Start: 2013-04-30End: 2015-12-31Target: 40Updated: 2015-03-17

Related Papers

Associations of blood RNA biomarkers and circulating tumour cells in patients with previously untreated metastatic colorectal cancer.

2025-04-21

Association of Circulating Tumor Cells and Tumor Molecular Profile With Clinical Outcomes in Patients With Previously Untreated Metastatic Colorectal Cancer: A Pooled Analysis of the Phase III VISNÚ-1 and Phase II VISNÚ-2 Randomized Trials.

2023-02-214 citations

Association Between Baseline Circulating Tumor Cells, Molecular Tumor Profiling, and Clinical Characteristics in a Large Cohort of Chemo-naïve Metastatic Colorectal Cancer Patients Prospectively Collected.

2020-03-0628 citations

Dermatux: Phase IV trial of C-FOLFIRI in 1<sup>st</sup>-line metastatic colorectal cancer receiving a pre-defined skin care.

Journal of Clinical Oncology2016-05-20

Cell-free circulating tumour DNA as a tool for monitoring response to anti-EGFR therapies of mCCR.

Journal of Clinical Oncology2016-05-20