Folate

DRUG17 trials

Conditions

AdenomasAlzheimer's DiseaseAutistic DisorderColorectal CancerDementiaGastric Intestinal MetaplasiaHIVKidney Failure, Chronic

Phase 2

Phase 2 Trial of Bevacizumab in Combination With Pemetrexed

CompletedNCT00227019

Heather WakeleeLung Cancer, Neoplasm Metastasis, Non-small Cell Lung Cancer (NSCLC)

Start: 2006-03-31End: 2016-12-31Updated: 2017-03-06

A Study of the Safety and Efficacy of Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis Receiving Methotrexate

CompletedNCT00243412

Genentech, Inc.Rheumatoid Arthritis

Start: 2005-08-31End: 2009-02-28Updated: 2011-10-07

Aspirin/Folate Prevention of Large Bowel Polyps

CompletedNCT00272324

Dartmouth-Hitchcock Medical CenterAdenomas, Colorectal Cancer, Polyps

Start: 1992-02-29End: 2007-01-31Target: 1121Updated: 2020-03-13

Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis

TerminatedNCT00298272

BiogenRheumatoid Arthritis

Start: 2006-05-31End: 2011-07-31Updated: 2015-09-28

Exercise Intolerance in Renal Failure

CompletedNCT01356966

Emory UniversityKidney Failure, Chronic

Start: 2011-05-31End: 2014-05-31Updated: 2015-06-01

Effect of Vitamin B on Plasma Neurofilament Light Protein (NFL) in HIV-infected Individuals With Increased Plasma Homocysteine

NCT02773147

Göteborg UniversityHIV

Start: 2016-04-30End: 2018-11-30Target: 60Updated: 2018-01-02

Phase 3

VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study)

CompletedNCT00056225

National Institute on Aging (NIA)Alzheimer's Disease

Start: 2003-01-31End: 2007-06-30Updated: 2009-06-12

A Study of Retreatment With Rituximab in Patients With Rheumatoid Arthritis Receiving Background Methotrexate

CompletedNCT00266227

Genentech, Inc.Rheumatoid Arthritis

Start: 2006-01-31Updated: 2013-10-25

A Study to Evaluate the Safety and Efficacy of Rituximab in Combination With Methotrexate Compared to Methotrexate Alone in Patients With Active Rheumatoid Arthritis

CompletedNCT00299130

Genentech, Inc.Rheumatoid Arthritis

Start: 2005-10-31End: 2013-07-31Updated: 2017-04-17

A Study to Evaluate Rituximab in Combination With Methotrexate in Methotrexate-Naive Patients With Active Rheumatoid Arthritis

CompletedNCT00299104

Genentech, Inc.Rheumatoid Arthritis

Start: 2006-01-31End: 2013-07-31Updated: 2017-07-28

Phase 4

Can Oral Vitamin B12 and Folate Supplementation Preserve Cognitive Function of Patients With Early Dementia?

CompletedNCT00164970

Chinese University of Hong KongDementia

Start: 2004-10-31End: 2008-12-31Target: 166Updated: 2009-02-03

Folate Supplementation in Schizophrenia

CompletedNCT00249288

Massachusetts General HospitalSchizophrenia

Start: 2003-12-31End: 2008-06-30Updated: 2018-04-05

A Study of MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Therapies.

CompletedNCT00462345

Hoffmann-La RocheRheumatoid Arthritis

Start: 2007-06-30End: 2009-07-31Updated: 2014-11-04

A Study of RoActemra/Actemra (Tocilizumab) Versus Adalimumab in Combination With Methotrexate (MTX) in Patients With Moderate to Severe Active Rheumatoid Arthritis And an Inadequate Response to Treatment With Only One Tumor Necrosis Factor (TNF)-Inhibitor

TerminatedNCT01283971

Hoffmann-La RocheRheumatoid Arthritis

Start: 2011-05-31End: 2012-08-31Updated: 2014-02-10

Metformin Efficacy and Safety for Gastric Intestinal Metaplasia

CompletedNCT05288153

Xijing Hospital of Digestive DiseasesGastric Intestinal Metaplasia

Start: 2022-04-01End: 2023-10-31Updated: 2024-09-23

Unknown Phase

Treating Oxidative Stress and the Metabolic Pathology of Autism

CompletedNCT00572741

Arkansas Children's Hospital Research InstituteAutistic Disorder

Start: 2008-06-30End: 2016-04-30Updated: 2016-05-05

Fish Oil and Folate Supplementation During Pregnancy

CompletedNCT01180933

Ludwig-Maximilians - University of MunichNeurological Development, Perinatal DHA and Folate Status

Start: 2001-11-30End: 2013-03-31Updated: 2014-07-30

Chinese Medical Journal2025-06-16

Proliferation, apoptosis and their regulatory protein expression in colorectal adenomas and serrated lesions

PLoS ONE2021-11-117 citations

Proliferation, apoptosis and their regulatory protein expression in colorectal adenomas and serrated lesions

Carolina Digital Repository (University of North Carolina at Chapel Hill)2021-01-01

Folic acid supplementation and risk of colorectal neoplasia during long-term follow-up of a randomized clinical trial.

2019-10-0117 citations

Tofacitinib Versus Biologic Treatments in Patients With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Tumor Necrosis Factor Inhibitors: Results From a Network Meta-analysis.

2016-11-2436 citations

Folate and long-chain polyunsaturated fatty acid supplementation during pregnancy has long-term effects on the attention system of 8.5-y-old offspring: a randomized controlled trial.

2015-11-1132 citations

Sustained inhibition of progressive joint damage with rituximab plus methotrexate in early active rheumatoid arthritis: 2-year results from the randomised controlled trial IMAGE.

2011-10-1981 citations

Effects of prenatal fish-oil and 5-methyltetrahydrofolate supplementation on cognitive development of children at 6.5 y of age.

2011-08-1770 citations

Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: the IMAGE trial.

2010-10-11192 citations

Uracil misincorporation into DNA and folic acid supplementation.

2009-11-1818 citations

High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial.

2008-10-01358 citations

Folate

Sponsors

Conditions

Phase 2

Phase 3

Phase 4

Unknown Phase

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