Fluorouracil Injection

DRUG5 trials

Conditions

Advanced Solid TumorsBreast NeoplasmsColorectal NeoplasmsGastro-Intestinal Intraepithelial NeoplasiaHead and Neck NeoplasmsLocally Advanced Unresectable Esophageal Squamous Cell CarcinomaLocally advanced rectal cancerLocally recurrent rectal cancer

Phase 1

A Study of SHR-1826 for Injection in Combination With Other Antitumor Therapies in Subjects With Solid Tumors

RecruitingNCT06703177

Suzhou Suncadia Biopharmaceuticals Co., Ltd.Advanced Solid Tumors

Start: 2025-02-18End: 2027-07-01Target: 876Updated: 2025-12-03

Phase 2

Neo-adjuvant FOLFOXIRI and chemoradiotherapy for high risk (“ugly”) locally advanced rectal cancer.

Active, not recruitingCTIS2023-509758-74-00

Catharina Ziekenhuis StichtingLocally advanced rectal cancer

Start: 2021-07-21Target: 128Updated: 2024-03-25

Phase 3

A Phase III, Randomized, Double-Blind, Placebo Controlled, Multi-Center, International Study of Durvalumab Given Concurrently With Definitive Chemoradiation Therapy in Patients With Locally Advanced, Unresectable Esophageal Squamous Cell Carcinoma (KUNLUN).

Active, not recruitingCTIS2023-506413-22-00

Astrazeneca ABLocally Advanced Unresectable Esophageal Squamous Cell Carcinoma

Start: 2021-03-31Target: 48Updated: 2026-01-09

Multicentre, open-label, randomized, controlled, parallel arms clinical trial of induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as neoadjuvant treatment for locally recurrent rectal cancer (PelvEx II)

RecruitingCTIS2024-512526-28-00

Catharina Ziekenhuis StichtingLocally recurrent rectal cancer

Start: 2020-10-28Target: 364Updated: 2026-01-19

Phase 4

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

RecruitingNCT07158164

Rutgers, The State University of New JerseyBreast Neoplasms, Colorectal Neoplasms, Gastro-Intestinal Intraepithelial Neoplasia +1