Fludara 50 mg powder for solution for injection or infusion.
Sponsors
Autolus Limited, Ospedale Pediatrico Bambino Gesu'
Conditions
B-cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL).Relapsed/refractory B-cell Acute Lymphoblastic LeukemiaRelapsed/refractory CD7+ T-cell Acute Lymphoblastic Leukemia/Lymphoma
Phase 1
A Single-Arm, Open-Label, Multicenter, Phase 1b/2 Study Evaluating the Safety and Efficacy of AUTO1 (obecabtagene autoleucel [obe-cel]) in Pediatric Patients with CD19-positive Relapsed/Refractory (R/R) B cell Acute Lymphoblastic Leukemia (B ALL) or R/R Aggressive Mature B Cell Non–Hodgkin Lymphoma (B NHL)
RecruitingCTIS2023-506307-26-00
Start: 2024-05-22Target: 14Updated: 2026-01-09
Phase I clinical trial on the use of fresh, allogeneic, second-generation CD19-CAR T cells for treatment of children and young adult with relapsed/refractory B-cell Acute Lymphoblastic Leukemia
RecruitingCTIS2023-508420-36-00
Start: 2024-04-23Target: 24Updated: 2024-04-23
Phase I/II study of anti-CD7 Chimeric Antigen Receptor-Expressing T cells in pediatric patients/young adult affected by relapsed/refractory CD7+ T-cell Acute Lymphoblastic Leukemia/Lymphoma
RecruitingCTIS2023-508355-39-00
Start: 2024-04-20Target: 26Updated: 2024-10-16