Flucelvax

BIOLOGICAL6 trials

Sponsors

University of Rochester, Centers for Disease Control and Prevention, National Institute of Allergy and Infectious Diseases (NIAID), University of Alabama at Birmingham, National Heart, Lung, and Blood Institute (NHLBI)

Conditions

Healthy VolunteerInfluenzaLymphomaSeasonal Influenza

Phase 1

First-in-Human Clinical Trial of a Mosaic Quadrivalent Influenza Vaccine Compared With a Licensed Inactivated Seasonal QIV in Healthy Adults

CompletedNCT04896086

National Institute of Allergy and Infectious Diseases (NIAID)Influenza, Seasonal Influenza

Start: 2021-05-24End: 2024-01-25Updated: 2025-04-27

Phase 2

Systems Analyses of the Immune Response to the Seasonal Influenza Vaccine

CompletedNCT04025580

National Institute of Allergy and Infectious Diseases (NIAID)Healthy Volunteer

Start: 2019-10-02End: 2023-01-31Updated: 2024-01-02

Phase 4

Comparison of Three Licensed Influenza Vaccines

CompletedNCT03068949

University of RochesterInfluenza

Start: 2015-10-28End: 2021-06-30Updated: 2021-11-30

Immunogenicity Trial of Egg- Versus Non-Egg-Based Influenza Vaccines Among HCP

CompletedNCT03722589

Centers for Disease Control and PreventionInfluenza

Start: 2018-09-12End: 2020-07-31Updated: 2024-07-22

B Cell and Antibody Response to Seasonal Influenza Vaccines in Younger and Older Adults

RecruitingNCT04101838

University of Alabama at BirminghamInfluenza

Start: 2021-04-01End: 2026-05-31Target: 50Updated: 2025-09-17

Vaccine Responses in Patients With B Cell Malignancies

RecruitingNCT05170399

National Heart, Lung, and Blood Institute (NHLBI)Lymphoma

Start: 2022-09-14End: 2026-08-16Target: 500Updated: 2026-02-05

Related Papers

Mosaic quadrivalent influenza vaccine single nanoparticle characterization.

2024-02-249 citations

Redirecting antibody responses from egg-adapted epitopes following repeat vaccination with recombinant or cell culture-based versus egg-based influenza vaccines.

2024-01-0414 citations

Effect of Repeat Vaccination on Immunogenicity of Quadrivalent Cell-Culture and Recombinant Influenza Vaccines Among Healthcare Personnel Aged 18–64 Years: A Randomized, Open-Label Trial

Clinical Infectious Diseases2022-08-2914 citations

Comparison of the Immunogenicity of Cell Culture-Based and Recombinant Quadrivalent Influenza Vaccines to Conventional Egg-Based Quadrivalent Influenza Vaccines Among Healthcare Personnel Aged 18–64 Years: A Randomized Open-Label Trial

Clinical Infectious Diseases2021-06-2441 citations

Comparison of Human H3N2 Antibody Responses Elicited by Egg-Based, Cell-Based, and Recombinant Protein–Based Influenza Vaccines During the 2017–2018 Season

Clinical Infectious Diseases2019-10-0447 citations