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Floxuridine (FUDR)

DRUG6 trials

Sponsors

Memorial Sloan Kettering Cancer Center, Corewell Health West, Benaroya Research Institute

Conditions

CholangiocarcinomaCholangiocellular CarcinomaCholangiolar CarcinomaColorectal Adenocarcinoma Metastatic to the LiverColorectal CancerIntrahepatic CholangiocarcinomaLiver MetastasesPancreatic Adenocarcinoma

Phase 2

Hepatic Arterial Infusion (HAI) With Floxuridine (FUDR) and Dexamethasone (Dex) Combined With Systemic Gemcitabine and Oxaliplatin in Patients With Unresectable Intrahepatic Cholangiocarcinoma (ICC)
CompletedNCT01862315
Memorial Sloan Kettering Cancer CenterCholangiocellular Carcinoma, Cholangiolar Carcinoma, Intrahepatic Cholangiocarcinoma +1
Start: 2013-05-31End: 2025-03-18Updated: 2025-03-19
Study of Chemotherapy With or Without Hepatic Arterial Infusion for Patients With Unresectable Metastatic Colorectal Cancer to the Liver
WithdrawnNCT03069950
Memorial Sloan Kettering Cancer CenterColorectal Adenocarcinoma Metastatic to the Liver
Start: 2017-02-28End: 2019-05-16Updated: 2019-05-21
A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma
CompletedNCT03693807
Memorial Sloan Kettering Cancer CenterCholangiocarcinoma, Colorectal Cancer
Start: 2018-10-18End: 2024-06-27Updated: 2026-02-06
Hepatic Artery Infusional Floxuridine to Treat Pancreatic Cancer Liver Metastases
Active, not recruitingNCT03856658
Corewell Health WestLiver Metastases, Pancreatic Adenocarcinoma
Start: 2019-02-05End: 2025-12-31Updated: 2025-06-17
A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma
NCT04668976
Benaroya Research InstituteCholangiocarcinoma, Colorectal Cancer
Start: 2020-11-25End: 2024-12-31Target: 100Updated: 2020-12-21
Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery
RecruitingNCT04891289
Memorial Sloan Kettering Cancer CenterIntrahepatic Cholangiocarcinoma
Start: 2021-05-07End: 2027-05-01Target: 164Updated: 2026-04-01

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