FIT

DIAGNOSTIC_TEST14 trials

Sponsors

The First Affiliated Hospital of Guangxi Medical University, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Yale University, VA Office of Research and Development, Lewai Sharki Abdulaziz, MSc PhD

Conditions

AdenomaAdenomatous Polyp of ColonAdenomatous PolypsAdvanced AdenomaColonrectal cancer and precancerous lesionsColorectal AdenomaColorectal Adenoma and CarcinomaColorectal Cancer

Early Phase 1

Screening for Colorectal Cancer in Average and High Risk Population

CompletedNCT04017845

Lewai Sharki Abdulaziz, MSc PhDAdenomatous Polyp of Colon, Colorectal Cancer, Colorectal Neoplasms

Start: 2015-04-01End: 2017-10-30Updated: 2019-09-04

A multicenter study of septin9 combined with fecal occult blood screening for colorectal cancer in Guangxi

RecruitingChiCTR2000038319

The First Affiliated Hospital of Guangxi Medical UniversityColorectal cancer

Start: 2019-09-01Updated: 2020-12-14

Clinical study of fecal SDC2 / TFPI2 methylation combined with FIT in the detection of colorectal cancer and precancerous lesions

Active, not recruitingChiCTR2100049651

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyColonrectal cancer and precancerous lesions

Start: 2021-08-15Updated: 2022-04-19

Phase 2

Clinical Trial of Abstinence-Linked Money Management

CompletedNCT00536900

Yale UniversitySubstance Abuse

Start: 2004-06-30End: 2009-04-30Updated: 2020-03-30

Unknown Phase

Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)

Active, not recruitingNCT01239082

VA Office of Research and DevelopmentColorectal Cancer

Start: 2012-04-30End: 2028-12-01Updated: 2025-11-10

Multitarget Stool FIT-DNA Study for Colorectal Cancer Early Screening in China

CompletedNCT04287335

Zhejiang UniversityAdenoma, Adenomatous Polyps, Advanced Adenoma +1

Start: 2018-09-18End: 2020-09-13Updated: 2020-12-08

Combining Risk Factors and Faecal Immunochemical Testing in Colorectal Cancer Screening: a Randomized Controlled Trial

CompletedNCT04490551

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Colorectal Adenoma, Colorectal Adenoma and Carcinoma, Colorectal Cancer +2

Start: 2019-12-05End: 2021-06-01Updated: 2021-08-13

Colorectal Cancer Screening Using Stool DNA-based SDC2 and SFRP2 Methylation Test in China

Changhai HospitalAdenoma, Adenomatous Polyps, Advanced Adenoma +3

Start: 2020-08-31End: 2021-08-31Target: 4800Updated: 2020-08-18

FIT Families Multicomponent Obesity Intervention for African American Adolescents

Active, not recruitingNCT04974554

Medical University of South CarolinaMetabolic Syndrome, Obesity, Childhood

Start: 2021-05-01End: 2026-11-30Target: 360Updated: 2026-02-09

Diagnostic Accuracy of M3 in Predicting Colorectal Advanced Adenoma Recurrence (M3-AA)

RecruitingNCT05144152

Chinese University of Hong KongAdvanced Adenoma, Colorectal Adenoma, Colorectal Polyp

Start: 2021-12-13End: 2025-06-15Target: 600Updated: 2024-08-27

A Study on a Blood-based Dual-target Test for CRC Detection

CompletedNCT05508503

Changhai HospitalColorectal Adenoma, Colorectal Cancer

Start: 2022-10-21End: 2023-08-11Updated: 2024-02-16

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

RecruitingNCT05612347

Dartmouth-Hitchcock Medical CenterColorectal Adenoma, Colorectal Cancer, Colorectal Neoplasms +2

Start: 2023-06-14End: 2035-12-31Target: 8946Updated: 2025-09-23

China Colorectal Cancer Screening Trial 2 (C-Cost2)

Not yet recruitingNCT07090304

Zhejiang UniversityAdvanced Adenoma, Colorectal Cancer

Start: 2025-07-31End: 2028-11-30Target: 7504Updated: 2025-07-29

China Colorectal Cancer Screening Trial 1 (C-Cost1)

RecruitingNCT07090291

Zhejiang UniversityAdvanced Adenoma, Colorectal Cancer

Start: 2025-08-08End: 2035-07-01Target: 60300Updated: 2026-04-01

Related Papers

Evaluation of a plasma cell-free DNA methylation test for colorectal cancer diagnosis: a multicenter clinical study

BMC Medicine2024-10-083 citations

Study protocol for clinical trial of the FIT Families multicomponent obesity intervention for African American adolescents and their caregivers: Next step from the ORBIT initiative

BMJ Open2024-02-01

Diagnostic yield of a risk model versus faecal immunochemical test only: a randomised controlled trial in a colorectal cancer screening programme.

2023-07-191 citations

Methylated Septin9 has moderate diagnostic value in colorectal cancer detection in Chinese population: a multicenter study.

2022-05-1117 citations

Comparative evaluation of novel screening strategies for colorectal cancer screening in China (TARGET-C): a study protocol for a multicentre randomised controlled trial

BMJ Open2019-04-0129 citations

Colonoscopy vs. Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM): Rationale for Study Design

The American Journal of Gastroenterology2017-10-10115 citations