First cohort

3 trials

Sponsors

Mie University Hospital, Kyushu University Hospital, Department of Immuno-gene Therapy, Mie University Graduate School of Medicine

Conditions

Therapy-resistant esophageal canceradvanced solid tumors which already have finished available standard therapies.

Phase 1

Adoptive transfer of lymphocytes transduced with MAGE-A4-specific TCR gene for therapy-resistant esophageal cancer

Active, not recruitingJPRN-UMIN000002395

Mie University HospitalTherapy-resistant esophageal cancer

Start: 2009-08-01Target: 9Updated: 2026-06-29

A phase 1 study of adoptive immunotherapy using autologous RNF43 peptide pulse dendritic cells and RNF43 peptide specifically activated lymphocytes in patients with advanced solid tumors

Active, not recruitingJPRN-UMIN000003945

Kyushu University Hospitaladvanced solid tumors which already have finished available standard therapies.

Start: 2009-04-01Target: 10Updated: 2026-06-29

Adoptive transfer of lymphocytes transduced with MAGE-A4-specific TCR gene following lymphodepleting conditioning for therapy-resistant esophageal cancer

Active, not recruitingJPRN-UMIN000010729

Department of Immuno-gene Therapy, Mie University Graduate School of MedicineTherapy-resistant esophageal cancer

Start: 2013-05-15Target: 12Updated: 2026-06-29