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Fibrinogen Concentrate Human

DRUG5 trials

Sponsors

Peking Union Medical College Hospital, Angel Augusto Perez Calatayud, IRCCS Policlinico S. Donato, Centre Hospitalier Universitaire de Saint Etienne, Brno University Hospital

Conditions

BleedingCardiac DefectCoagulopathy, ConsumptionCongenital Heart DiseaseFibrinogenFibrinogen; Deficiency, AcquiredFibrinogenolysis; HemorrhageFibrinogenopenia; Acquired

Phase 2

ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery
TerminatedNCT04434001
IRCCS Policlinico S. DonatoBleeding, Cardiac Defect, Congenital Heart Disease +4
Start: 2020-02-27End: 2021-06-30Updated: 2021-11-03
Administration of Fibrinogen Concentrate for Refractory Bleeding
TerminatedNCT05091684
Centre Hospitalier Universitaire de Saint EtienneBleeding, Hematological Patients, Platelet Refractoriness
Start: 2022-02-10End: 2023-06-27Updated: 2025-12-23

Phase 4

The Effects of Fibrinogen Concentrate Infusion on Blood Loss and Allogeneic Blood Conservation in Scoliosis Surgery
CompletedNCT03183479
Peking Union Medical College HospitalBleeding, Scoliosis; Adolescence, Surgery
Start: 2017-06-14End: 2019-08-31Updated: 2020-03-02
Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery
NCT05391412
Brno University HospitalBleeding, Coagulopathy, Consumption, Fibrinogen +1
Start: 2022-06-06End: 2023-09-30Target: 32Updated: 2023-03-28

Unknown Phase

Patient Blood Management for Massive Obstetric Hemorrhage
CompletedNCT03784794
Angel Augusto Perez CalatayudFibrinogen; Deficiency, Acquired, Fibrinogenolysis; Hemorrhage, Massive Hemorrhage +2
Start: 2018-11-01End: 2020-12-30Updated: 2021-06-08

Related Papers

Effect of prophylactic fibrinogen concentrate in scoliosis surgery (EFISS): a randomised pilot trial.
2025-10-07
Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery (EFISS): a study protocol of two-arm, randomised trial
BMJ Open2023-05-013 citations