FFP

BIOLOGICAL4 trials

Sponsors

Helsinki University Central Hospital, Erasmus Medical Center, Northwell Health, CSL Behring

Conditions

BleedingCardiac DiseaseComplex Cardiovascular Surgery With Cardiopulmonary BypassCovid19Postpartum HaemorrhageSurgery

Phase 2

Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery

RecruitingNCT07032792

Northwell HealthBleeding, Cardiac Disease, Surgery

Start: 2025-11-03End: 2029-11-01Target: 140Updated: 2026-03-11

Phase 3

Early Convalescent Plasma Therapy for High-risk Patients With COVID-19 in Primary Care (the CoV-Early Study)

TerminatedNCT04589949

Erasmus Medical CenterCovid19

Start: 2020-10-12End: 2022-03-01Updated: 2022-04-01

Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

RecruitingNCT07094087

CSL BehringComplex Cardiovascular Surgery With Cardiopulmonary Bypass

Start: 2025-09-15End: 2027-05-05Target: 200Updated: 2026-08-18

Phase 4

PCC and Fibrinogen Compared With FFP in PPH

WithdrawnNCT01910675

Helsinki University Central HospitalPostpartum Haemorrhage

Start: 2013-07-31End: 2018-10-31Updated: 2018-10-10

Related Papers

Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients.

2022-05-1123 citations