FindTrial
Sign In

Ferric derisomaltose

DRUG14 trials

Sponsors

University of Glasgow, Michael Kremke, Pharmacosmos A/S, AHS Cancer Control Alberta, Women and Infants Hospital of Rhode Island

Conditions

Acute Heart FailureAdultAnemiaAnemia PostoperativeAnemia, Iron DeficiencyCardiac SurgeryChronic Heart FailureGynecologic Cancer

Early Phase 1

Monoferric for Prenatal Iron Deficiency
RecruitingNCT05763043
Oregon Health and Science UniversityObstetric Labor Complications
Start: 2024-01-18End: 2028-10-31Target: 80Updated: 2024-09-19

Phase 3

Multi-center Trial of Ferric Derisomaltose in Children 0 to <18 Years of Age With Iron Deficiency Anemia
RecruitingNCT05179226
Pharmacosmos A/SIron Deficiency, Anaemia in Children
Start: 2022-11-28End: 2026-04-30Target: 200Updated: 2025-05-22
Ferric Derisomaltose and Outcomes in the Recovery of Gynecologic Oncology: ERAS (Enhanced Recovery After Surgery)
RecruitingNCT05407987
AHS Cancer Control AlbertaAnemia, Gynecologic Cancer, Iron-deficiency
Start: 2025-04-08End: 2026-12-30Target: 82Updated: 2025-04-25
Intravenous Versus Oral Iron for Treating Iron-Deficiency Anemia in Pregnancy
RecruitingNCT05462704
Women and Infants Hospital of Rhode IslandIron Deficiency Anemia, Pregnancy
Start: 2023-01-17End: 2027-03-31Target: 300Updated: 2025-06-10
Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure
RecruitingNCT06929806
Pharmacosmos A/SChronic Heart Failure, Iron Deficiencies
Start: 2025-05-01End: 2027-12-01Target: 1900Updated: 2025-07-23

Phase 4

Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN
CompletedNCT02642562
University of GlasgowChronic Heart Failure, Iron Deficiency, Left Ventricular Systolic Dysfunction
Start: 2016-08-31End: 2022-08-26Target: 1160Updated: 2022-10-28
A Clinical Trial Assessing the Efficacy of Intravenous Iron for the Treatment of Anemia Following Cardiac Surgery
CompletedNCT04608539
Michael KremkeAnemia Postoperative
Start: 2021-05-21End: 2023-06-27Updated: 2023-06-28
The Effects of Ferric Derisomaltose on Postoperative Anemia in Spinal Deformity Surgery
RecruitingNCT05714007
Peking Union Medical College HospitalAdult, Perioperative Anemia, Spinal Deformity +1
Start: 2023-08-31End: 2025-12-31Target: 120Updated: 2025-06-13
Iron Deficiency Anemia (IDA) and the Brain
RecruitingNCT05929729
Children's Hospital Los AngelesAnemia, Anemia, Iron Deficiency, IDA - Iron Deficiency Anemia +1
Start: 2023-12-07End: 2028-09-01Target: 120Updated: 2024-10-30
The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life(COREVIVE-HFrEF)
NCT05971732
China-Japan Friendship HospitalAcute Heart Failure, Heart Failure With Reduced Ejection Fraction, Iron Deficiency
Start: 2023-08-01End: 2025-08-01Target: 146Updated: 2023-08-15
The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life
NCT05991128
China-Japan Friendship HospitalAcute Heart Failure, Heart Failure With Preserved Ejection Fraction, Iron Deficiencies
Start: 2023-08-01End: 2025-08-01Target: 170Updated: 2023-09-26
The Effects of Intravenous Iron on Mobility in Elderly Patients Following Hip Fracture Surgery
RecruitingNCT06898814
Soren OvergaardAnemia, Hip Fracture
Start: 2025-06-09End: 2027-09-14Target: 210Updated: 2025-12-10
Postoperative Intravenous Ferric Derisomaltose for Prevention of Long-term Anemia After Cardiac Surgery
Not yet recruitingNCT07238972
Yonsei UniversityAnemia, Cardiac Surgery, Heart Valve Diseases +2
Start: 2025-12-31End: 2030-10-31Target: 180Updated: 2025-11-20

Unknown Phase

IRONHEART: Intravenous Iron in Non-ischaemic Heart Failure
RecruitingNCT06542822
University Hospital Southampton NHS Foundation TrustHeart Failure, Iron Deficiencies
Start: 2024-04-15End: 2027-02-28Target: 16Updated: 2024-08-07

Related Papers

Single-dose IV ferric derisomaltose improves hematologic and patient-reported outcomes in pregnant individuals with iron deficiency anemia
Blood2025-11-03
Age-stratified effects of intravenous ferric derisomaltose in heart failure with iron deficiency: insights from the IRONMAN trial.
2025-06-131 citations
Effect of Correcting Iron Deficiency on the Risk of Serious Infection in Heart Failure: Insights from the IRONMAN Trial
European Journal of Heart Failure2024-10-259 citations
Adjudication of Hospitalizations and Deaths in the IRONMAN Trial of Intravenous Iron for Heart Failure.
2024-10-018 citations
Administration of Ferric Derisomaltose for Iron Deficiency and Heart Failure During Hospital Admission or at the Clinic – Insights from the IRONMAN Trial
European Journal of Heart Failure2024-07-30
Effects of ferric derisomaltose on postoperative anaemia in adult spinal deformity surgery: a study protocol for a randomised controlled trial
BMJ Open2024-01-011 citations
The Impact of Iron Deficiency Anemia on Cerebrovascular Physiology, Brain Structure, and Cognitive Function in Otherwise Healthy Women
Blood2023-11-022 citations
Ferric derisomaltose and Outcomes in the Recovery of Gynecologic oncology: ERAS (Enhanced Recovery After Surgery) (FORGE) – a protocol for a pilot randomised double-blinded parallel-group placebo-controlled study of the feasibility and efficacy of intravenous ferric derisomaltose to correct preoperative iron-deficiency anaemia in patients undergoing gynaecological oncology surgery
BMJ Open2023-11-014 citations
Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial.
2022-11-05223 citations
Rationale and design of a randomised trial of intravenous iron in patients with heart failure
Heart2022-08-1013 citations