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Fasting-mimicking diet

DIETARY_SUPPLEMENT5 trials

Sponsors

Indiana University, Marina Garassino, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Universitaire Ziekenhuizen KU Leuven, Sun Yat-sen University

Conditions

Advanced LKB1-inactive Lung AdenocarcinomaBreast CancerNon-small Cell Lung CancerTriple Negative Breast Cancer (TNBC), Early SettingTriple-negative Breast Cancer

Phase 2

Metformin Plus/Minus Fasting Mimicking Diet to Target the Metabolic Vulnerabilities of LKB1-inactive Lung Adenocarcinoma
NCT03709147
Marina GarassinoAdvanced LKB1-inactive Lung Adenocarcinoma
Start: 2018-10-30End: 2023-09-10Target: 64Updated: 2020-11-16
Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer
NCT04248998
Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoTriple-negative Breast Cancer
Start: 2020-05-05End: 2024-05-01Updated: 2023-01-18
LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Therapy in Patients With Triple Negative Breast Cancer
RecruitingNCT06831955
Universitaire Ziekenhuizen KU LeuvenTriple Negative Breast Cancer (TNBC), Early Setting
Start: 2026-02-01End: 2031-09-01Target: 356Updated: 2026-03-20
FMD and Neoadjuvant Chemo-immunotherapy in TNBC
Not yet recruitingNCT07378306
Sun Yat-sen UniversityBreast Cancer
Start: 2026-02-01End: 2029-12-31Target: 80Updated: 2026-01-30

Unknown Phase

Fasting-mimicking Diet With Chemo-immunotherapy in Non-small Cell Lung Cancer (NSCLC)
CompletedNCT03700437
Indiana UniversityNon-small Cell Lung Cancer
Start: 2018-11-02End: 2022-03-23Updated: 2022-05-12

Related Papers

Abstract 2008: Fasting induces ferroptosis by modulating lipid metabolism in breast cancer.
Cancer Research2026-04-03
Early downmodulation of tumor glycolysis predicts response to fasting-mimicking diet in triple-negative breast cancer patients.
2024-12-178 citations
Abstract RF02-07: Precocious modulation of metabolic and immunological parameters predicts tumor response to fasting-mimicking diet plus chemotherapy in patients with early stage TNBC
Cancer Research2024-05-022 citations