Faldaprevir
Sponsors
Boehringer Ingelheim, Presidio Pharmaceuticals, Inc., Trek Therapeutics, PBC
Conditions
Chronic Hepatitis CHealthyHepatitis C (HCV)Hepatitis C Genotype 1Hepatitis C Genotype 4Hepatitis C Viral InfectionHepatitis C, ChronicRenal Insufficiency
Phase 1
Investigation of Food Effect and Gastric ph Increase on the Bioavailability of Faldapravir
CompletedNCT01694706
Start: 2012-09-30End: 2012-12-31Updated: 2015-07-30
Investigation of Faldaprevir Effect on Pharmacokinetics of Raltegravir
CompletedNCT01785160
Start: 2013-02-28End: 2013-03-31Updated: 2015-08-03
Investigation of Interactions Between Faldaprevir, Itraconazole, Atorvastatin and Rosuvastatin
CompletedNCT01795937
Start: 2013-02-28End: 2013-03-31Updated: 2015-08-03
Effect of BI 207127 + Faldaprevir on Blood Levels of Oral Contraceptives Containing Ethinylestradiol and Levonorgestrel
TerminatedNCT01941615
Start: 2013-11-30End: 2014-01-31Updated: 2016-04-11
Pharmacokinetics, Safety and Tolerability of the Combination of BI 207127 and Faldaprevir in Renal Impaired Patients
TerminatedNCT01957657
Start: 2013-10-31End: 2013-12-31Updated: 2016-04-11
Thorough QT Study to Evaluate the Effects of BI 207127 (Deleobuvir) Combined With Faldaprevir on Cardiac Safety Parameters in Healthy Subjects.
CompletedNCT01965431
Start: 2013-10-31End: 2014-01-31Updated: 2016-04-14
Investigation of Potential Drug-drug Interactions Between Faldaprevir and the Immunosuppressant Drugs Cyclosporine or Tacrolimus
CompletedNCT02016625
Start: 2013-12-31End: 2014-04-30Updated: 2016-05-23
Phase 2
BI 207127 / Faldaprevir Combination Therapy in Hepatic Impairment (Child-Pugh B) Patients With Genotype 1b Chronic Hepatitis C Infection: HCVerso3
CompletedNCT01830127
Start: 2013-04-30End: 2014-10-31Updated: 2015-11-20
Study of PPI-668, BI 207127 and Faldaprevir, With and Without Ribavirin, in the Treatment of Chronic Hepatitis C
CompletedNCT01859962
Start: 2013-05-31End: 2014-12-31Updated: 2015-11-25
A Study of Faldaprevir, Ribavirin and TD-6450 in Participants With Genotype 4 Hepatitis C Virus Infection
CompletedNCT02593162
Start: 2015-10-31End: 2016-12-31Updated: 2017-01-30
A Study of Faldaprevir, TD-6450 and Other Antivirals in Participants With Genotype 1b Hepatitis C Virus Infection
CompletedNCT02716428
Start: 2016-05-31End: 2017-09-30Updated: 2017-10-17